Radiohalogens for imaging and therapy

MJ Adam, DS Wilbur - Chemical Society Reviews, 2005 - pubs.rsc.org
Radiohalogens play a very important role in radiopharmaceuticals used for medical imaging
(now referred to as molecular imaging) and therapy applications. Development of new …

Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

In vivo targeting and positron emission tomography imaging of tumor vasculature with 66Ga-labeled nano-graphene

H Hong, Y Zhang, JW Engle, TR Nayak, CP Theuer… - Biomaterials, 2012 - Elsevier
The goal of this study was to employ nano-graphene for tumor targeting in an animal tumor
model, and quantitatively evaluate the pharmacokinetics and tumor targeting efficacy …

[HTML][HTML] Quantitative imaging for targeted radionuclide therapy dosimetry-technical review

T Li, ECI Ao, B Lambert, B Brans, S Vandenberghe… - Theranostics, 2017 - ncbi.nlm.nih.gov
Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However,
in order to deliver the required dose to the tumor, minimize potential toxicity in normal …

Positron range in PET imaging: non-conventional isotopes

L Jødal, C Le Loirec, C Champion - Physics in Medicine & …, 2014 - iopscience.iop.org
In addition to conventional short-lived radionuclides, longer-lived isotopes are becoming
increasingly important to positron emission tomography (PET). The longer half-life both …

Very high specific activity 66/68Ga from zinc targets for PET

JW Engle, V Lopez-Rodriguez… - Applied Radiation and …, 2012 - Elsevier
This work describes the production of very high specific activity 66/68Ga from natZn (p, n)
and 66Zn (p, n) using proton irradiations between 7 and 16MeV, with emphasis on 66Ga for …

Fluorine-18-Labeled Benzamide Analogues for Imaging the σ2 Receptor Status of Solid Tumors with Positron Emission Tomography

Z Tu, J Xu, LA Jones, S Li, C Dumstorff… - Journal of medicinal …, 2007 - ACS Publications
A series of fluorine-containing benzamide analogs was synthesized and evaluated as
candidate ligands for positron emission tomography (PET) imaging of the sigma-2 (σ2) …

Comparison of scandium-44 g with other PET radionuclides in pre-clinical PET phantom imaging

S Ferguson, HS Jans, M Wuest, T Riauka, F Wuest - EJNMMI physics, 2019 - Springer
Purpose The decay characteristics of radionuclides in PET studies can impact image
reconstruction. 44g Sc has been the topic of recent research due to potential theranostic …

Positron range modeling for statistical PET image reconstruction

B Bai, A Ruangma, R Laforest, YC Tai… - 2003 IEEE Nuclear …, 2003 - ieeexplore.ieee.org
Positron range is one of the factors that fundamentally limits the spatial resolution of PET
images. With the higher resolution of small animal imaging systems and increased interest …

Instrumentation aspects of animal PET

YC Tai, R Laforest - Annu. Rev. Biomed. Eng., 2005 - annualreviews.org
▪ Abstract Biological research has been accelerated by the development of noninvasive
imaging techniques and by use of genetically engineered mice to model human diseases …