Chemistry and biology of ferritin

M Plays, S Müller, R Rodriguez - Metallomics, 2021 - academic.oup.com
Iron is an essential element required by cells and has been described as a key player in
ferroptosis. Ferritin operates as a fundamental iron storage protein in cells forming …

Reactive oxygen species in the world ocean and their impacts on marine ecosystems

JJ Morris, AL Rose, Z Lu - Redox Biology, 2022 - Elsevier
Reactive oxygen species (ROS) are omnipresent in the ocean, originating from both
biological (eg, unbalanced metabolism or stress) and non-biological processes (eg …

The ferritins: molecular properties, iron storage function and cellular regulation

PM Harrison, P Arosio - Biochimica et biophysica acta (BBA)-bioenergetics, 1996 - Elsevier
The iron storage protein, ferritin, plays a key role in iron metabolism. Its ability to sequester
the element gives ferritin the dual functions of iron detoxification and iron reserve. The …

Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis

J Yi, S Wu, S Tan, Y Qin, X Wang, J Jiang, H Liu… - Cell death …, 2021 - nature.com
Berberine (BBR) has been explored as a potential anti-liver fibrosis agent, but the
underlying mechanisms are unknown. In the current study, we aimed to investigate the …

[LIVRE][B] Chemical dissolution of metal oxides

MA Blesa - 2018 - taylorfrancis.com
The dissolution behaviour of metal oxides has applications in many scientific fields, each
with its own jargon and methodological approach. Any scientist interested in this subject …

Iron therapy for preterm infants

R Rao, MK Georgieff - Clinics in perinatology, 2009 - Elsevier
Preterm infants are at risk for both iron deficiency and iron overload. The role of iron in
multiple organ functions suggests that iron supplementation is essential for the preterm …

Model studies of the iron-catalysed Haber-Weiss cycle and the ascorbate-driven Fenton reaction

MJ Burkitt, BC Gilbert - Free radical research communications, 1990 - Taylor & Francis
Complementary hydroxylation assays and stopped-flow esr techniques have been
employed in the investigation of the effect of various iron chelators (of chemical, biological …

Radicals from “Good's” buffers

JK Grady, ND Chasteen, DC Harris - Analytical biochemistry, 1988 - Elsevier
Oxidative deposition of iron in ferritin or the autoxidation of iron in the absence of protein
produces radicals from Good's buffers. Radical species are formed from the piperazine ring …

Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity

O Gakh, S Park, G Liu, L Macomber… - Human molecular …, 2006 - academic.oup.com
Friedreich ataxia is a severe autosomal-recessive disease characterized by
neurodegeneration, cardiomyopathy and diabetes, resulting from reduced synthesis of the …

Effects of positive iron status at a cellular level

JM McCord - Nutrition Reviews, 1996 - academic.oup.com
The human body is not equipped to eliminate excess iron. As a result, cells continously store
excess absorbed iron in a complex with the protein ferritin. This poses no great threat under …