Consequences of disturbing manganese homeostasis

J Baj, W Flieger, A Barbachowska, B Kowalska… - International Journal of …, 2023 - mdpi.com
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …

Aluminium in the human brain: routes of penetration, toxicity, and resulting complications

Ł Bryliński, K Kostelecka, F Woliński, P Duda… - International Journal of …, 2023 - mdpi.com
Aluminium (Al) is the most ubiquitous metal in the Earth's crust. Even though its toxicity is
well-documented, the role of Al in the pathogenesis of several neurological diseases …

[HTML][HTML] The role of environmental trace element toxicants on autism: A medical biogeochemistry perspective

SM Awadh, ZM Yaseen, MS Al-Suwaiyan - … and environmental safety, 2023 - Elsevier
Since genetic factors alone cannot explain most cases of Autism, the environmental factors
are worth investigating as they play an essential role in the development of some cases of …

Exposing the role of metals in neurological disorders: a focus on manganese

H Kim, FE Harrison, M Aschner, AB Bowman - Trends in molecular …, 2022 - cell.com
Metals are ubiquitous chemical entities involved in a myriad of biological processes. Despite
their integral role in sustaining life, overexposure can lead to deleterious neurological …

A systematic literature review on the association between exposures to toxic elements and an autism spectrum disorder

A Shiani, K Sharafi, AK Omer, A Kiani… - Science of The Total …, 2023 - Elsevier
Background and aim Autism spectrum disorder (ASD) is a neurodevelopmental illness
characterized by difficulties in social communication and repetitive behaviors. There have …

[HTML][HTML] Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: A systematic review and meta-analysis

M Ding, S Shi, S Qie, J Li, X ** - Frontiers in pediatrics, 2023 - frontiersin.org
Background Studies have found that toxic heavy metals exposure could induce the
generation of reactive oxygen species (ROS), and is of epigenetic effect, which might be …

Update of the risk assessment of inorganic arsenic in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission asked EFSA to update its 2009 risk assessment on
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …

Plant food bioactives and its effects on gut microbiota profile modulation for better brain health and functioning in Autism Spectrum Disorder individuals: A review

H Shanmugam, S Ganguly, B Priya - Food frontiers, 2022 - Wiley Online Library
Recent advances in gut microbiota researches are establishing the association between
food, gut microbiota, and brain health. Previously unknown communication networks …

Trace Elements Levels in Major Depressive Disorder—Evaluation of Potential Threats and Possible Therapeutic Approaches

J Baj, J Bargieł, J Cabaj, B Skierkowski… - International Journal of …, 2023 - mdpi.com
The multifactorial etiology of major depressive disorder (MDD) includes biological,
environmental, genetic, and psychological aspects. Recently, there has been an increasing …

Urinary metabolomics using gas chromatography-mass spectrometry: potential biomarkers for autism spectrum disorder

ZUN Khan, P Chand, H Majid, S Ahmed, AH Khan… - BMC neurology, 2022 - Springer
Background Diagnosis of autism spectrum disorder (ASD) is generally made phenotypically
and the hunt for ASD-biomarkers continues. The purpose of this study was to compare urine …