Cognitive intra-individual variability in cognitively healthy APOE ε4 carriers, mild cognitive impairment, and Alzheimer's disease: A meta-analysis

SL Aita, VA Del Bene, DL Knapp, CE Demming… - Neuropsychology …, 2024 - Springer
Intra-individual variability (IIV) quantifies an individual's scatter in performances across a test
battery (dispersion) or across reaction times within a single task (consistency). No studies …

Traumatic brain Injury, seizures, and cognitive impairment among older adults

Y Zhu, J Williams, K Beyene, JF Trani… - JAMA Network …, 2024 - jamanetwork.com
Importance Traumatic brain injury (TBI), seizures, and dementia increase with age. There is
a gap in understanding the associations of TBI, seizures, and medications such as …

Around the EQUATOR with Clin‐STAR: Prediction modeling opportunities and challenges in aging research

WJ Deardorff, LG Diaz‐Ramirez… - Journal of the …, 2024 - Wiley Online Library
Abstract The 2015 Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis (TRIPOD) Statement was published to improve reporting …

[HTML][HTML] Pathologic correlates of aging-related tau astrogliopathy: ARTAG is associated with LATE-NC and cerebrovascular pathologies, but not with ADNC

Y Katsumata, X Wu, KZ Aung, K Gauthreaux… - Neurobiology of …, 2024 - Elsevier
Age-related tau astrogliopathy (ARTAG) is detectable in the brains of over one-third of
autopsied persons beyond age 80, but the pathoetiology of ARTAG is poorly understood …

Referral Sources Across Racial and Ethnic Groups at Alzheimer's Disease Research Centers

CK Chan, KA Lane, S Gao… - Journal of …, 2024 - journals.sagepub.com
Background: Despite the need to increase engagement of underrepresented groups (URG)
in Alzheimer's disease and related dementias (ADRD) studies, enrollment remains low …

Cognitive dispersion and its functional relevance in behavioral variant frontotemporal dementia and prodromal behavioral variant frontotemporal dementia.

TA Webber, SP Woods, SA Lorkiewicz… - …, 2024 - psycnet.apa.org
Objective: Executive dysfunction is characteristic of behavioral variant frontotemporal
dementia (bvFTD) but can be challenging to detect. Dispersion-based intraindividual …

Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer's Coordinating Center database

DC Woodworth, KM Nguyen, L Sordo… - Acta …, 2024 - Springer
TDP-43 proteinopathy is a salient neuropathologic feature in a subset of frontotemporal
lobar degeneration (FTLD-TDP), in amyotrophic lateral sclerosis (ALS-TDP), and in limbic …

Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer's …

Y Katsumata, X Wu, KZ Aung, DW Fardo… - Acta …, 2024 - Springer
Pure limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes
(pure LATE-NC) is a term used to describe brains with LATE-NC but lacking intermediate or …

Amyloid-β predominant Alzheimer's disease neuropathologic change

GG Kovacs, Y Katsumata, X Wu, KZ Aung, DW Fardo… - Brain, 2025 - academic.oup.com
Different subsets of Alzheimer's disease neuropathologic change (ADNC), including the
intriguing set of individuals with severe/widespread amyloid-β (Aβ) plaques but no/mild tau …

Extracellular Vesicles for Alzheimer Disease and Dementia Diagnosis

HB Taha - medRxiv, 2024 - medrxiv.org
Accurate differential diagnosis of dementia disorders including Alzheimer disease (AD),
frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), Parkinson disease …