Blastic plasmacytoid dendritic cell neoplasm: diagnostic criteria and therapeutical approaches

L Pagano, CG Valentini, S Grammatico… - British journal of …, 2016 - Wiley Online Library
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy
derived from the precursors of plamacytoid dendritic cells, with an aggressive clinical course …

Blastic plasmacytoid dendritic cell neoplasm: state of the art and prospects

MR Sapienza, A Pileri, E Derenzini, F Melle, G Motta… - Cancers, 2019 - mdpi.com
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare tumour, which
usually affects elderly males and presents in the skin with frequent involvement of the bone …

CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis

R Lande, EY Lee, R Palazzo, B Marinari… - Nature …, 2019 - nature.com
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis and
vasculopathy. CXCL4 represents an early serum biomarker of severe SSc and likely …

Dual expression of TCF4 and CD123 is highly sensitive and specific for blastic plasmacytoid dendritic cell neoplasm

N Sukswai, PP Aung, CC Yin, S Li… - The American journal …, 2019 - journals.lww.com
The diagnosis of blastic plasmacytoid dendritic cell neoplasm (BPDCN) has been based on
the expression status of multiple markers, including CD123. TCF4 was discovered recently …

Immunophenotypic characterization of reactive and neoplastic plasmacytoid dendritic cells permits establishment of a ten-color flow cytometric panel for initial workup …

W Wang, JD Khoury, RN Miranda… - …, 2020 - pmc.ncbi.nlm.nih.gov
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic neoplasm
whose immunophenotype remains incompletely characterized, particularly with regards to …

TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow

K Alayed, KP Patel, S Konoplev… - American journal of …, 2013 - Wiley Online Library
Distinguishing blastic plasmacytoid dendritic cell neoplasm (BPDCN) from acute myeloid
leukemia (AML) is gaining increased importance because of emerging differences in …

Transcriptional control of dendritic cell development and functions

L Amon, CHK Lehmann, A Baranska, J Schoen… - International review of …, 2019 - Elsevier
Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …

[HTML][HTML] Neoplasms derived from plasmacytoid dendritic cells

F Facchetti, M Cigognetti, S Fisogni, G Rossi… - Modern Pathology, 2016 - Elsevier
Plasmacytoid dendritic cell neoplasms manifest in two clinically and pathologically distinct
forms. The first variant is represented by nodular aggregates of clonally expanded …

Intratumoral plasmacytoid dendritic cells as a poor prognostic factor for hepatocellular carcinoma following curative resection

ZJ Zhou, HY **n, J Li, ZQ Hu, CB Luo… - Cancer Immunology …, 2019 - Springer
Plasmacytoid dendritic cells (pDCs) are present in various primary and metastatic human
neoplasms; however, their clinical significance in hepatocellular carcinoma (HCC) is …

Blastic plasmacytoid dendritic cell neoplasm–current insights

S Venugopal, S Zhou, SM El Jamal, AA Lane… - … Myeloma and Leukemia, 2019 - Elsevier
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare clonal hematologic
malignancy of plasmacytoid dendritic cell precursors. The presentation and clinical course of …