Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

The standard of care (SOC) for high-grade gliomas (HGG) is maximally safe surgical
resection, followed by concurrent radiation therapy (RT) and temozolomide (TMZ) for 6 …

Glioblastoma multiforme (GBM) is one of the most fatal malignancies due to the existence of
blood-brain barrier (BBB) and the difficulty to maintain an effective drug accumulation in …

Gliomas, a prevalent category of primary malignant brain tumors, pose formidable clinical
challenges due to their invasive nature and limited treatment options. The current …

Nature has always inspired robotic designs and concepts. It is conceivable that biomimic
nanorobots will soon play a prominent role in medicine. The “Terminator” in the science …

Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

Glioma is a fatal brain tumor characterized by rapid proliferation and treatment resistance.
Ferroptosis is a newly discovered programmed cell death and plays a crucial role in the …

Background Tumor recurrence, the chief reason for poor prognosis of glioma, is largely
attributed to glioma stem cells (GSCs) and epithelial-mesenchymal transition (EMT) …

Glioma is the most common type of primary malignant tumor in the central nervous system
with limited treatment satisfaction. Finding new therapeutic targets has remained a major …

Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor. Despite new
knowledges on the genetic characteristics, conventional therapy for GBM, tumor resection …