Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
Why won't it stop? The dynamics of benzodiazepine resistance in status epilepticus
Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society
T Glauser, S Shinnar, D Gloss, B Alldredge… - Epilepsy …, 2016 - journals.sagepub.com
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
Intramuscular versus intravenous therapy for prehospital status epilepticus
Background Early termination of prolonged seizures with intravenous administration of
benzodiazepines improves outcomes. For faster and more reliable administration …
benzodiazepines improves outcomes. For faster and more reliable administration …
[HTML][HTML] Seizure cluster: definition, prevalence, consequences, and management
Purpose To summarize definitions, prevalence, risk factors, consequences, and acute
management of seizure clusters using rescue medications. Methods We searched MEDLINE …
management of seizure clusters using rescue medications. Methods We searched MEDLINE …
Pharmacotherapy for status epilepticus
Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
Guidelines for the diagnosis and treatment of acute encephalopathy in childhood
The cardinal symptom of acute encephalopathy is impairment of consciousness of acute
onset during the course of an infectious disease, with duration and severity meeting defined …
onset during the course of an infectious disease, with duration and severity meeting defined …
Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children
A McTague, T Martland… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Tonic‐clonic convulsions and convulsive status epilepticus (currently defined
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …
Anticonvulsant therapy for status epilepticus
Background Status epilepticus is a medical emergency associated with significant mortality
and morbidity that requires immediate and effective treatment. Objectives (1) To determine …
and morbidity that requires immediate and effective treatment. Objectives (1) To determine …
Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study
E Lahat, M Goldman, J Barr, T Bistritzer, M Berkovitch - Bmj, 2000 - bmj.com
Objective: To compare the safety and efficacy of midazolam given intranasally with
diazepam given intravenously in the treatment of children with prolonged febrile seizures …
diazepam given intravenously in the treatment of children with prolonged febrile seizures …