[HTML][HTML] The clinical outcome of Hurler syndrome after stem cell transplantation

M Aldenhoven, JJ Boelens, TJ de Koning - Biology of Blood and Marrow …, 2008 - Elsevier
Hurler syndrome (HS) is a severe inborn error of metabolism causing progressive multi-
system morbidity and death in early childhood. At present, stem cell transplantation (SCT) is …

Current international perspectives on hematopoietic stem cell transplantation for inherited metabolic disorders

JJ Boelens, VK Prasad, J Tolar, RF Wynn… - Pediatric …, 2010 - pediatric.theclinics.com
Inherited metabolic disorders (IMD) or inborn errors of metabolism are a diverse group of
diseases arising from genetic defects in lysosomal enzymes or peroxisomal function …

Outcomes of hematopoietic stem cell transplantation for Hurler's syndrome in Europe: a risk factor analysis for graft failure

JJ Boelens, RF Wynn, A O'meara, P Veys… - Bone marrow …, 2007 - nature.com
Abstract Hurler's syndrome (HS), the most severe form of mucopolysaccharidosis type-I,
causes progressive deterioration of the central nervous system and death in childhood …

The performance of laminin-containing cryogel scaffolds in neural tissue regeneration

M Jurga, MB Dainiak, A Sarnowska, A Jablonska… - Biomaterials, 2011 - Elsevier
Currently, there are no effective therapies to restore lost brain neurons, although rapid
progress in stem cell biology and biomaterials development provides new tools for …

Mannitol facilitates neurotrophic factor up‐regulation and behavioural recovery in neonatal hypoxic‐ischaemic rats with human umbilical cord blood grafts

T Yasuhara, K Hara, M Maki, L Xu, G Yu… - Journal of cellular …, 2010 - Wiley Online Library
We recently demonstrated that blood–brain barrier permeabilization using mannitol
enhances the therapeutic efficacy of systemically administered human umbilical cord blood …

Plasma membrane proteomics of tumor spheres identify CD166 as a novel marker for cancer stem-like cells in head and neck squamous cell carcinoma

M Yan, X Yang, L Wang, D Clark, H Zuo, D Ye… - Molecular & Cellular …, 2013 - ASBMB
Patients with advanced head and neck squamous cell carcinoma (HNSCC) have a poor
prognosis with the currently available therapy, and tumor recurrence is frequently observed …

[HTML][HTML] The potential of umbilical cord blood multipotent stem cells for nonhematopoietic tissue and cell regeneration

C van de Ven, D Collins, MB Bradley, E Morris… - Experimental …, 2007 - Elsevier
Stem cells have been isolated from human embryos, fetal tissue, umbilical cord blood
(UCB), and also from “adult” sources. Adult stem cells are found in many tissues of the body …

Umbilical cord blood: a unique source of pluripotent stem cells for regenerative medicine

DT Harris, I Rogers - Current stem cell research & therapy, 2007 - ingentaconnect.com
It is estimated that almost 1 in 3 individuals in the United States might benefit from
regenerative medicine therapy. Unfortunately, embryonic stem (ES) cell therapies are …

[HTML][HTML] Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome

JJ Boelens, V Rocha, M Aldenhoven, R Wynn… - Biology of Blood and …, 2009 - Elsevier
Allogeneic stem cell transplantation (SCT) is considered effective in preventing disease
progression in patients with Hurler syndrome (HS). Unrelated umbilical cord blood (UCB) …

Transplantation of umbilical cord blood stem cells for treating spinal cord injury

DH Park, JH Lee, CV Borlongan, PR Sanberg… - Stem Cell Reviews and …, 2011 - Springer
Spinal cord injury (SCI) develops primary and secondary damage to neural tissue and this
often results in permanent disability of the motor and sensory functions. However, there is …