In silico investigation of skin permeation is an important but also computationally demanding
problem. To resolve all scales involved in full detail will not only require exascale computing …

Offering insights into the behavior of applications at higher scale, performance models are
useful for finding performance bugs and tuning the system. Extra-P, a tool for automated …

Skin modeling is an ongoing research area that highly benefits from modern parallel
algorithms. This article aims at applying shape optimization to compute cell size and …

The scenario of an impacting drop onto a film is highly relevant in many natural and
technical systems. A fundamental and often required parameter of these interactions is the …

In this paper we present a shape optimization scheme which utilizes the alternating direction
method of multipliers (ADMM) to approximate a direction of steepest descent in $ W^{1,\infty} …

The primary breakup of liquid jets plays an important role in fuel injection for combustion
engines and gas turbines. Due to the ambient conditions the liquid also evaporates during …

Liquid jet break-up appears in many technical applications, as well as in nature. It consists of
complex physical processes, which happen on very small scales in space and time. This …

Many libraries in the HPC field use sophisticated algorithms with clear theoretical scalability
expectations. However, hardware constraints or programming bugs may sometimes render …

Many existing applications suffer from inherent scalability limitations that will prevent them
from running at exascale. Current tuning practices, which rely on diagnostic experiments …

Many scientific research questions such as the drug diffusion through the upper part of the
human skin are formulated in terms of partial differential equations and their solution is …