Molecular Pathogenesis of Infections Caused by Legionella pneumophila

HJ Newton, DKY Ang, IR Van Driel… - Clinical microbiology …, 2010 - Am Soc Microbiol
The genus Legionella contains more than 50 species, of which at least 24 have been
associated with human infection. The best-characterized member of the genus, Legionella …

Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host

B Singh, C Fleury, F Jalalvand… - FEMS microbiology …, 2012 - academic.oup.com
Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

A complex interplay between the extracellular matrix and the innate immune response to microbial pathogens

H Tomlin, AM Piccinini - Immunology, 2018 - Wiley Online Library
The role of the host extracellular matrix (ECM) in infection tends to be neglected. However,
the complex interactions between invading pathogens, host tissues and immune cells occur …

Microbial Peptidyl-Prolyl cis/trans Isomerases (PPIases): Virulence Factors and Potential Alternative Drug Targets

CM Ünal, M Steinert - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases
(PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at …

Factors Mediating Environmental Biofilm Formation by Legionella pneumophila

A Abu Khweek, AO Amer - Frontiers in cellular and infection …, 2018 - frontiersin.org
Legionella pneumophila (L. pneumophila) is an opportunistic waterborne pathogen and the
causative agent for Legionnaires' disease, which is transmitted to humans via inhalation of …

The guinea pig as a model of infectious diseases

DJ Padilla-Carlin, DN McMurray… - Comparative …, 2008 - ingentaconnect.com
The words' guinea pig'are synonymous with scientific experimentation, but much less is
known about this species than many other laboratory animals. This animal model has been …

Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the …

M Kang, YP Ko, X Liang, CL Ross, Q Liu… - Journal of biological …, 2013 - ASBMB
Members of a family of collagen-binding microbial surface components recognizing
adhesive matrix molecules (MSCRAMMs) from Gram-positive bacteria are established …

Mycobacterium tuberculosis Primary Infection and Dissemination: A Critical Role for Alveolar Epithelial Cells

MB Ryndak, S Laal - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
Globally, tuberculosis (TB) has reemerged as a major cause of morbidity and mortality,
despite the use of the Mycobacterium bovis BCG vaccine and intensive attempts to improve …

Proteomic Characterization of the Whole Secretome of Legionella pneumophila and Functional Analysis of Outer Membrane Vesicles

F Galka, SN Wai, H Kusch, S Engelmann… - Infection and …, 2008 - Am Soc Microbiol
Secretion of effector molecules is one of the major mechanisms by which the intracellular
human pathogen Legionella pneumophila interacts with host cells during infection. Specific …

Legionella pneumophila: The Journey from the Environment to the Blood

V Iliadi, J Staykova, S Iliadis, I Konstantinidou… - Journal of Clinical …, 2022 - mdpi.com
An outbreak of a potentially fatal form of pneumonia in 1976 and in the annual convention of
the American Legion was the first time that Legionella spp. was identified. Thereafter, the …