Adding biological meaning to human protein-protein interactions identified by yeast two-hybrid screenings: A guide through bioinformatics tools

J Felgueiras, JV Silva, M Fardilha - Journal of proteomics, 2018 - Elsevier
Abstract “A man is known by the company he keeps” is a popular expression that perfectly
fits proteins. A common approach to characterize the function of a target protein is to identify …

[HTML][HTML] Death processes in bovine theca and granulosa cells modelled and analysed using a systems biology approach

MJ McEvoy, E Sinderewicz, L Creedon… - International Journal of …, 2021 - mdpi.com
In this paper, newly discovered mechanisms of atresia and cell death processes in bovine
ovarian follicles are investigated. For this purpose the mRNA expression of receptor …

Tissue-specific subcellular localization prediction using multi-label Markov random fields

L Zhu, R Hofestädt, M Ester - IEEE/ACM transactions on …, 2019 - ieeexplore.ieee.org
The understanding of subcellular localization (SCL) of proteins and proteome variation in
the different tissues and organs of the human body are two crucial aspects for increasing our …

A 20S proteasome receptor for degradation of intrinsically disordered proteins

A Biran, N Myers, J Adler, K Broennimann, N Reuven… - BioRxiv, 2017 - biorxiv.org
Degradation of intrinsically disordered proteins (IDPs) by the 20S proteasome, unlike
ubiquitin-dependent 26S proteasomal degradation, does not require proteasomal targeting …

Topological Analysis of Cancer Protein Subnetwork in Deubiquitinase (DUB) Interactome

N Zulkifle - … and Biomedical Engineering: 8th International Work …, 2020 - Springer
Ubiquitination pathway regulates many cellular events that underlie the development of
various cancer types. This led to tremendous interest in exploration of cancer therapeutics …

[КНИГА][B] Annotating Human Interactome to Predict Pathways and Systematically Analyzing Network Rewiring in Cancer Across Multiple Tissues

S Rahmati - 2018 - search.proquest.com
Human protein-protein interaction (PPI) networks are essential in regulating most cellular
processes and their disruption can cause complex diseases such as cancer. Currently …

[PDF][PDF] Context-specific subcellular localization prediction: Leveraging protein interaction networks and scientific texts

L Zhu - 2018 - core.ac.uk
One essential task in proteomics analysis is to explore the functions of proteins in
conducting and regulating the activities at the subcellular level. Compartmentalization of …