Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …
important roles in growth and development, tissue and organ regeneration, as well as …
Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
Interconnection between metabolism and cell cycle in cancer
Cell cycle progression and division is regulated by checkpoint controls and sequential
activation of cyclin-dependent kinases (CDKs). Understanding of how these events occur in …
activation of cyclin-dependent kinases (CDKs). Understanding of how these events occur in …
[HTML][HTML] Mechanisms of endothelial regeneration and vascular repair and their application to regenerative medicine
Endothelial barrier integrity is required for maintaining vascular homeostasis and fluid
balance between the circulation and surrounding tissues and for preventing the …
balance between the circulation and surrounding tissues and for preventing the …
Arginine dependence of tumor cells: targeting a chink in cancer's armor
Arginine, one among the 20 most common natural amino acids, has a pivotal role in cellular
physiology as it is being involved in numerous cellular metabolic and signaling pathways …
physiology as it is being involved in numerous cellular metabolic and signaling pathways …
[HTML][HTML] Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin
Q Li, Z Zhu, L Wang, Y Lin, H Fang, J Lei, T Cao… - Theranostics, 2021 - ncbi.nlm.nih.gov
Vascular endothelial cells (ECs) are increasingly recognized as active players in
intercellular crosstalk more than passive linings of a conduit for nutrition delivery. Yet, their …
intercellular crosstalk more than passive linings of a conduit for nutrition delivery. Yet, their …
How endothelial cells adapt their metabolism to form vessels in tumors
Endothelial cells (ECs) line blood vessels, ie, vital conduits for oxygen and nutrient delivery
to distant tissues. While mostly present as quiescent “phalanx” cells throughout adult life …
to distant tissues. While mostly present as quiescent “phalanx” cells throughout adult life …
Transient introduction of miR-294 in the heart promotes cardiomyocyte cell cycle reentry after injury
A Borden, J Kurian, E Nickoloff, Y Yang… - Circulation …, 2019 - Am Heart Assoc
Rationale: Embryonic heart is characterized of rapidly dividing cardiomyocytes required to
build a working myocardium. Cardiomyocytes retain some proliferative capacity in the …
build a working myocardium. Cardiomyocytes retain some proliferative capacity in the …
Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells
B Yetkin-Arik, IMC Vogels, N Neyazi, V Van Duinen… - Scientific reports, 2019 - nature.com
Formation of new blood vessels by differentiated endothelial tip cells, stalk cells, and
phalanx cells during angiogenesis is an energy-demanding process. How these specialized …
phalanx cells during angiogenesis is an energy-demanding process. How these specialized …
Metabolic hallmarks of liver regeneration
Despite the crucial role of cell metabolism in biological processes, particularly cell division,
metabolic aspects of liver regeneration are not well defined. Better understanding of the …
metabolic aspects of liver regeneration are not well defined. Better understanding of the …