Glioblastoma multiforme is one of the calamitous primary glial brain tumors with extensive
heterogeneity at cellular and molecular levels. While maximal surgical resection trailed by …

Simple Summary Glioblastoma stem cells are a unique population of tumor cells that
contribute to tumor growth, invasion, and resistance to chemotherapy and radiation therapy …

Background Sorafenib resistance poses therapeutic challenges in HCC treatment, in which
cancer stem cells (CSCs) plays a crucial role. CRISPR/Cas9 can be utilized as a potential …

A glioblastoma (GBM) is one of the most aggressive, infiltrative, and treatment-resistant
malignancies of the central nervous system (CNS). The current standard of care for GBMs …

Cancer is one of the leading causes of mortality worldwide. Numerous strategies have been
developed for cancer treatment. Metastasis, heterogeneity, chemotherapy resistance …

Ionizing radiation (IR) has been shown to play a crucial role in the treatment of glioblastoma
(GBM; grade IV) and non-small-cell lung cancer (NSCLC). Nevertheless, recent studies …

Telomerase reverse transcriptase (TERT), a core part of telomerase, has been known for a
long time only for its telomere lengthening function by reverse transcription of RNA template …

Glioblastoma (GB) is one of the most adverse diagnoses in oncology. Complex current
treatment results in a median survival of 15 months. Resistance to treatment is associated …

Background Cancer stem cells have been implicated in tumor relapse, tumor invasion, and
cancer therapy resistance in high-grade gliomas; thus, characterizing cancer stem cell …

Glioblastoma (GBM) is the most devastating and frequent type of primary brain tumor with
high morbidity and mortality. Despite the use of surgical resection followed by radio-and …