Adolescence is a period of life that encompasses biological maturation and profound
change in social roles. It is also a period associated with the onset of mental health …

Adolescence is a time of significant neurocognitive development. Prolonged maturation of
prefrontal cortex (PFC) through adolescence has been found to support improvements in …

Aging is characterized by the decline in many of the individual's capabilities. It has been
recognized that the brain undergoes structural and functional changes during aging that are …

Developmental changes in prefrontal cortex (PFC) excitatory (glutamatergic, Glu) and
inhibitory (gamma-aminobutryic acid, GABA) neurotransmitter balance (E: I) have been …

Adolescence has been hypothesized to be a critical period for the development of human
association cortex and higher-order cognition. A defining feature of critical period …

Recently, politicians and legislative bodies have cited neurodevelopmental literature to
argue that brain immaturity undermines decision-making regarding gender-affirming care …

Adolescence is a time during which we transition to independence, explore new activities
and begin pursuit of major life goals. Goal-directed learning, in which we learn to perform …

Metabolites play important roles in brain development and their levels change rapidly in the
prenatal period and during infancy. Metabolite levels are thought to stabilize during …

A balanced excitation-inhibition ratio (E/I ratio) is critical for healthy brain function. Normative
development of cortex-wide E/I ratio remains unknown. Here, we noninvasively estimate a …

The development and refinement of neuronal circuitry allow for stabilized and efficient
neural recruitment, supporting adult-like behavioral performance. During adolescence, the …