Abstract Comprising~ 20% of the volume, water is a key determinant of the mechanical
behavior of cortical bone. It essentially exists in two general compartments: within pores and …

Background For biomechanical investigations on bone or bone implants, bone quality
represents an important potential bias. Several techniques for assessing bone quality have …

We describe the use of two-dimensional ultrashort echo time (2D UTE) sequences with
minimum TEs of 8μs to image and quantify cortical bone on a clinical 3T scanner. An …

In this study we describe the use of ultrashort echo time (UTE) magnetic resonance imaging
(MRI) to evaluate short and long T2* components as well as the water content of cortical …

Purpose To develop a method to assess volumetric cortical bone porosity in clinically
practical acquisition times by measuring the signal decay at only two echo times (TEs) as …

Water constitutes roughly a quarter of the cortical bone by volume yet can greatly influence
mechanical properties and tissue quality. There is a growing appreciation for how water can …

Since clinical measures of bone mineral density do not necessarily predict whether a person
will fracture a bone without an intervention, there is a need to find supplementary tools for …

Recent advancements in MRI have enabled clinical imaging of human cortical bone,
providing a potentially powerful new means for assessing bone health with molecular‐scale …

Advances in modern magnetic resonance imaging (MRI) pulse sequences have enabled
clinically practical cortical bone imaging. Human cortical bone is known to contain a …

Recent proton magnetic resonance (MR) spectroscopy studies have shown that cortical
bone exists as different components which have distinct transverse relaxation times (T2s) …