Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem,
with 10 million new cases diagnosed each year. Innate immunity plays an important role in …

Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs) have TIR intracellular
domains that engage two main signaling pathways, via the TIR-containing adaptors MyD88 …

Mycobacterium tuberculosis (Mtb) infection is a major international public health problem.
One‐third of the world′ s population is thought to have latent tuberculosis, a condition …

Mycobacteria are a genus of bacteria that range from the non‐pathogenic M ycobacterium
smegmatis to M ycobacterium tuberculosis, the causative agent of tuberculosis in humans …

Background Studies investigating the influence of toll-like receptor (TLR) polymorphisms
and tuberculosis susceptibility have yielded varying and often contradictory results in …

Background A large number of studies have investigated whether polymorphisms in the Toll-
like receptor (TLR) genes are implicated in susceptibility to tuberculosis (TB) in different …

Epidemiological data from the world health organization (WHO) show that Globally an
estimated 10 million (range, 8.9–11.0 million) people around the world were infected with TB …

The success of Mycobacterium tuberculosis as a pathogen relies on its ability to regulate the
host immune response. M. tuberculosis can manipulate adaptive T cell responses indirectly …

Background Gastric cancer (GC) is a progressive process initiated by Helicobacter pylori-
induced inflammation. Initial recognition of H. pylori involves Toll-like receptors (TLRs) …

Background Genetic factors are important contributors to the development of a wide range of
complex disease. Polymorphisms in genes encoding for toll-like receptors (TLRs) usually …