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Progress in nasal drug delivery systems
F Laffleur, B Bauer - International journal of pharmaceutics, 2021 - Elsevier
Most of the available drugs are usually administered orally (eg in tablets or capsules) or by
parenteral injection in the case of substances being destroyed in the gastric environment or …
parenteral injection in the case of substances being destroyed in the gastric environment or …
Biodegradable polymers in drug delivery and oral vaccination
Over the years biodegradable polymers have emerged as promising polymeric materials in
drug delivery and vaccination due to their fascinating properties like biocompatibility …
drug delivery and vaccination due to their fascinating properties like biocompatibility …
Recent advances in intranasal administration for brain-targeting delivery: a comprehensive review of lipid-based nanoparticles and stimuli-responsive gel formulations
J Koo, C Lim, KT Oh - International Journal of Nanomedicine, 2024 - Taylor & Francis
Addressing disorders related to the central nervous system (CNS) remains a complex
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …
Critical review of lipid-based nanoparticles as carriers of neuroprotective drugs and extracts
F Fernandes, M Dias-Teixeira, C Delerue-Matos… - Nanomaterials, 2021 - mdpi.com
The biggest obstacle to the treatment of diseases that affect the central nervous system
(CNS) is the passage of drugs across the blood-brain barrier (BBB), a physical barrier that …
(CNS) is the passage of drugs across the blood-brain barrier (BBB), a physical barrier that …
Design and evaluation of chrysin-loaded nanoemulsion against lithium/pilocarpine-induced status epilepticus in rats; emphasis on formulation, neuronal excitotoxicity …
Objectives The present study aims to formulate and evaluate the efficacy of chrysin-loaded
nanoemulsion (CH NE) against lithium/pilocarpine-induced epilepsy in rats, as well as …
nanoemulsion (CH NE) against lithium/pilocarpine-induced epilepsy in rats, as well as …
Anti-aging properties of phytoconstituents and phyto-nanoemulsions and their application in managing aging-related diseases
F Xue, X Li, L Qin, X Liu, C Li, B Adhikari - Advanced Drug Delivery …, 2021 - Elsevier
Aging is spontaneous and inevitable process in all living beings. It is a complex natural
phenomenon that manifests as a gradual decline of physiological functions and …
phenomenon that manifests as a gradual decline of physiological functions and …
Single step nanospray drying preparation technique of gabapentin-loaded nanoparticles-mediated brain delivery for effective treatment of PTZ-induced seizures
AH Salama, AAA Salama, M Elhabak - International Journal of …, 2021 - Elsevier
In the present study, gabapentin (GBP)-loaded chitosan nanosized particles were fabricated
applying the nanospray drying technique. Different preparation parameters (spray mesh …
applying the nanospray drying technique. Different preparation parameters (spray mesh …
Nutraceutical delivery through nano-emulsions: General aspects, recent applications and patented inventions
Nanostructured emulsions have a significant potential for encasing, transport and delivery of
hydrophilic and lipophilic nutraceuticals and other bioactive compounds by providing …
hydrophilic and lipophilic nutraceuticals and other bioactive compounds by providing …
Nose-to-brain drug delivery for the treatment of CNS disease: New development and strategies
L Du, L Chen, F Liu, W Wang, H Huang - International Review of …, 2023 - Elsevier
Delivering drugs to the brain has always been a challenging task due to the restrictive
properties of the blood-brain barrier (BBB). Intranasal delivery is therefore emerging as an …
properties of the blood-brain barrier (BBB). Intranasal delivery is therefore emerging as an …
Formulation and characterization of cholesterol-based nanoparticles of gabapentin protecting from retinal injury
Introduction This study aimed to prepare cholesterol and stearic acid-based solid lipid
nanoparticles of gabapentin (GAB-SLNs) for protection against streptozotocin (STZ)-induced …
nanoparticles of gabapentin (GAB-SLNs) for protection against streptozotocin (STZ)-induced …