The chick eye in vision research: An excellent model for the study of ocular disease

CE Wisely, JA Sayed, H Tamez, C Zelinka… - Progress in retinal and …, 2017 - Elsevier
The domestic chicken, Gallus gallus, serves as an excellent model for the study of a wide
range of ocular diseases and conditions. The purpose of this manuscript is to outline some …

Involvement of GABA transporters in atropine-treated myopic retina as revealed by iTRAQ quantitative proteomics

VA Barathi, SS Chaurasia, M Poidinger… - Journal of proteome …, 2014 - ACS Publications
Atropine, a muscarinic antagonist, is known to inhibit myopia progression in several animal
models and humans. However, the mode of action is not established yet. In this study, we …

Mass spectrometry‐based retina proteomics

L Prokai, K Zaman… - Mass spectrometry reviews, 2023 - Wiley Online Library
A subfield of neuroproteomics, retina proteomics has experienced a transformative growth
since its inception due to methodological advances in enabling chemical, biochemical, and …

SWATH based quantitative proteomics reveals significant lipid metabolism in early myopic guinea pig retina

J Bian, YH Sze, DYY Tse, CH To… - International journal of …, 2021 - mdpi.com
Most of the previous myopic animal studies employed a single-candidate approach and
lower resolution proteomics approaches that were difficult to detect minor changes, and …

Alteration of retinal metabolism and oxidative stress may implicate myopic eye growth: Evidence from discovery and targeted proteomics in an animal model

FJ Yu, TC Lam, AYH Sze, KK Li, RKM Chun… - Journal of …, 2020 - Elsevier
Myopia, the most common cause of impaired vision, may induce sight-threatening diseases
or ocular complications due to axial elongation. The exact mechanisms underlying myopia …

Alteration of EIF2 signaling, glycolysis, and dopamine secretion in form-deprived myopia in response to 1% atropine treatment: Evidence from interactive iTRAQ-MS …

Y Zhu, JF Bian, DQ Lu, CH To, CSY Lam… - Frontiers in …, 2022 - frontiersin.org
Purpose: Atropine, a non-selective muscarinic antagonist, effectively slows down myopia
progression in human adolescents and several animal models. However, the underlying …

Key role for inflammation-related signaling in the pathogenesis of myopia based on evidence from proteomics analysis

L Jiang, JHZ Koh, SHY Seah, YS Dan, Z Wang… - Scientific reports, 2024 - nature.com
The mechanisms underlying myopia pathogenesis are not well understood. Using publicly-
available human and animal datasets, we expound on the roles of known, implicated …

Isotope-coded protein label based quantitative proteomic analysis reveals significant up-regulation of apolipoprotein A1 and ovotransferrin in the myopic chick …

F Yu, TC Lam, L Liu, RK Chun, JK Cheung, K Li… - Scientific reports, 2017 - nature.com
This study used isotope-coded protein label (ICPL) quantitative proteomics and
bioinformatics analysis to examine changes in vitreous protein content and associated …

A proteomic approach to identify seminal plasma proteins in roosters (Gallus gallus domesticus)

M Marzoni, A Castillo, S Sagona, L Citti… - Animal reproduction …, 2013 - Elsevier
Considering the interest in avian semen processing and storage, the objective of this study
was to identify the domestic fowl seminal plasma proteins using two-dimensional gel …

Gene expression within the amacrine cell layer of chicks after myopic and hyperopic defocus

RS Ashby, MP Feldkaemper - Investigative ophthalmology & …, 2010 - iovs.arvojournals.org
Purpose.: Ocular growth is regulated locally by signals produced in the retina. The highly
heterogeneous nature of the retina may mask important changes in gene expression during …