Neurons are the largest cells in the body and form subcellular compartments such as axons
and dendrites. During both development and adulthood building blocks must be continually …

The formation of axon collateral branches from the pre-existing shafts of axons is an
important aspect of neurodevelopment and the response of the nervous system to injury …

Piloerection (goosebumps) requires concerted actions of the hair follicle, the arrector pili
muscle (APM), and the sympathetic nerve, providing a model to study interactions across …

Neutrophil extracellular traps (NETs) participate in the rapid inhibition and clearance of
pathogens during infection; however, the molecular regulation of NET formation remains …

TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate
morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon …

Endocrine fibroblast growth factor 23 (FGF23) is predominantly secreted by osteocytes and
facilitates renal phosphate excretion. However, FGF23 is also present in cerebrospinal fluid …

Directed outgrowth of axons is fundamental for the establishment of neuronal networks.
Axon outgrowth is guided by growth cones, highly motile structures enriched in filamentous …

Maintenance of cell population size is fundamental to the proper functioning of multicellular
organisms. Here, we describe a cell-intrinsic cell density–sensing pathway that enabled T …

Background Depression is a highly prevalent mental illness that severely impacts the quality
of life of affected individuals. Our recent studies demonstrated that diterpene ginkgolides …

The control of T cell survival is crucial for defense against infectious pathogens or emerging
cancers. Although the survival of peripheral naïve T cells has been proposed to be …