Targeting cytochrome P450 enzymes in ovarian cancers: new approaches to tumor-selective intervention
Over the past decade, there have been significant developments in treatment for ovarian
cancer, yet the lack of targeted therapy with few side effects still represents a major issue …
cancer, yet the lack of targeted therapy with few side effects still represents a major issue …
Recent advances of injectable in situ-forming hydrogels for preventing postoperative tumor recurrence
Z Wang, B Zhai, J Sun, X Zhang, J Zou, Y Shi… - Drug delivery, 2024 - Taylor & Francis
The unavoidable residual tumor tissue from surgery and the strong aggressiveness of tumor
cells pose challenges to the postoperative treatment of tumor patients, accompanied by in …
cells pose challenges to the postoperative treatment of tumor patients, accompanied by in …
Phytochemistry and Anticancer Effects of Mangrove (Rhizophora mucronata Lam.) Leaves and Stems Extract against Different Cancer Cell Lines
The biologically active components of the methanol extracts of R. mucronata were identified
using GC/MS. The anticancer effects of each methanol extract from the leaves and stem …
using GC/MS. The anticancer effects of each methanol extract from the leaves and stem …
Phytochemical Analysis and Profiling of Antitumor Compounds of Leaves and Stems of Calystegia silvatica (Kit.) Griseb.
Anti-tumor compounds from natural products are being investigated as possible alternatives
for cancer chemotherapeutics that have serious adverse effects and tumor resistance …
for cancer chemotherapeutics that have serious adverse effects and tumor resistance …
1‐Benzylimidazole attenuates the stemness of breast cancer cells through partially targeting CYP4Z1
H Qin, Y Zhou, H Liu, Y Yuan, Q Guo… - Environmental …, 2024 - Wiley Online Library
Abstract Cytochrome P450 (CYP) 4Z1 (CYP4Z1) has recently garnered much interest as its
expression predicts a poor prognosis and as a oncogene in breast cancer, and …
expression predicts a poor prognosis and as a oncogene in breast cancer, and …
Cytochrome 4Z1 expression connotes unfavorable prognosis in ovarian cancers
Background and Objective: Ovarian cancer is a leading cause of death in females. Since its
treatment is challenging and causes severe side effects, novel therapies are urgently …
treatment is challenging and causes severe side effects, novel therapies are urgently …
Improved methods for the detection of heme and protoporphyrin IX adducts and quantification of heme B from cytochrome P450 containing systems
RD Pelletier, AE Rettie, JP Kowalski - Journal of Chromatography B, 2023 - Elsevier
Heme B is a critical prosthetic group for the function of numerous proteins including the
cytochrome P450 (CYP) family of enzymes. CYP enzymes are involved in the metabolism of …
cytochrome P450 (CYP) family of enzymes. CYP enzymes are involved in the metabolism of …
Glypican-3 Differentiates Intraductal Carcinoma and Paget's Disease from Other Types of Breast Cancer
Background and Objectives: breast cancer remains the most common health burden
affecting females worldwide. Despite developments in breast cancer diagnostic approaches …
affecting females worldwide. Despite developments in breast cancer diagnostic approaches …
The fatty acid omega hydroxylase genes (CYP4 family) in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD): An RNA sequence …
C Leahy, N Osborne, L Shirota, P Rote, YK Lee… - Biochemical …, 2024 - Elsevier
Fatty acid omega hydroxylase P450s consist of enzymes that hydroxylate various chain-
length saturated and unsaturated fatty acids (FAs) and bioactive eicosanoid lipids. The …
length saturated and unsaturated fatty acids (FAs) and bioactive eicosanoid lipids. The …
Injectable hydrogel containing cowpea mosaic virus nanoparticles prevents colon cancer growth
Despite advances in laparoscopic surgery combined with neoadjuvant and adjuvant
therapy, colon cancer management remains challenging in oncology. Recurrence of …
therapy, colon cancer management remains challenging in oncology. Recurrence of …