Metal-based photosensitizers as inducers of regulated cell death mechanisms

Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …

Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

L Gourdon, K Cariou, G Gasser - Chemical Society Reviews, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) are therapeutic
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …

Metal–curcumin complexes in therapeutics: an approach to enhance pharmacological effects of curcumin

S Prasad, D DuBourdieu, A Srivastava… - International journal of …, 2021 - mdpi.com
Curcumin, an active component of the rhizome turmeric, has gained much attention as a
plant-based compound with pleiotropic pharmacological properties. It possesses anti …

Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands

LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …

Complexes of Zn (II) with a mixed tryptanthrin derivative and curcumin chelating ligands as new promising anticancer agents

ZF Wang, QX Nong, HL Yu, QP Qin, FH Pan… - Dalton …, 2022 - pubs.rsc.org
In this study, two novel curcumin (H-Cur)–tryptanthrin metal compounds—[Zn (TA) Cl2], ie,
Zn (TA), and [Zn (TA)(Cur)] Cl, ie, Zn (TAC)—were synthesized and investigated using 5-(bis …

Natural Products–Pyrazine Hybrids: A Review of Developments in Medicinal Chemistry

GQ Chen, HY Guo, ZS Quan, QK Shen, X Li, T Luan - Molecules, 2023 - mdpi.com
Pyrazine is a six-membered heterocyclic ring containing nitrogen, and many of its
derivatives are biologically active compounds. References have been downloaded through …

BODIPY-attached zinc (II) complexes of curcumin drug for visible light assisted photo-sensitization, cellular imaging and targeted PDT

A Bhattacharyya, A Jameei, AA Karande… - European Journal of …, 2021 - Elsevier
Boron-dipyrromethene (BODIPY) based photosensitizers as porphyrinoids and curcumin as
natural product possess exciting photophysical features suitable for theranostic applications …

A new class of nickel (ii) oxyquinoline–bipyridine complexes as potent anticancer agents induces apoptosis and autophagy in A549/DDP tumor cells through …

ZF Wang, QC Wei, JX Li, Z Zhou, SH Zhang - Dalton Transactions, 2022 - pubs.rsc.org
A new class of nickel (II) oxyquinoline–bipyridine complexes, namely,[Ni (La1) 2
(Lb6)](Ni1),[Ni (La1) 2 (Lb2)]· CH3OH (Ni2),[Ni (La7) 2 (Lb11)]· 2H2O (Ni3),[Ni (La1) 2 …

A dipyridophenazine Ni (II) dithiolene complex as a dual-acting cancer phototherapy agent activatable within the phototherapeutic window

T Sarkar, S Sahoo, S Neekhra, M Paul, S Biswas… - European Journal of …, 2023 - Elsevier
A combination of photodynamic therapy (PDT) and photothermal therapy (PTT) within the
phototherapeutic window (600–900 nm) can lead to significantly enhanced therapeutic …