Meta-analysis: exposure to early life stress and risk for depression in childhood and adolescence

J LeMoult, KL Humphreys, A Tracy… - Journal of the American …, 2020 - Elsevier
Objective Early life stress (ELS) is associated with increased risk for the development of
major depressive disorder (MDD) in adulthood; however, the degree to which ELS is …

Animal models of major depression: drawbacks and challenges

B Planchez, A Surget, C Belzung - Journal of Neural Transmission, 2019 - Springer
Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

Association between physical exercise and mental health in 1· 2 million individuals in the USA between 2011 and 2015: a cross-sectional study

SR Chekroud, R Gueorguieva, AB Zheutlin… - The lancet …, 2018 - thelancet.com
Background Exercise is known to be associated with reduced risk of all-cause mortality,
cardiovascular disease, stroke, and diabetes, but its association with mental health remains …

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

RS Duman, GK Aghajanian, G Sanacora, JH Krystal - Nature medicine, 2016 - nature.com
Depression is a common, devastating illness. Current pharmacotherapies help many
patients, but high rates of a partial response or no response, and the delayed onset of the …

A unified model of depression: Integrating clinical, cognitive, biological, and evolutionary perspectives

AT Beck, K Bredemeier - Clinical Psychological Science, 2016 - journals.sagepub.com
We propose that depression can be viewed as an adaptation to conserve energy after the
perceived loss of an investment in a vital resource such as a relationship, group identity, or …

Loneliness across the life span

P Qualter, J Vanhalst, R Harris… - Perspectives on …, 2015 - journals.sagepub.com
Most people have experienced loneliness and have been able to overcome it to reconnect
with other people. In the current review, we provide a life-span perspective on one …

How does social support enhance resilience in the trauma-exposed individual?

LM Sippel, RH Pietrzak, DS Charney, LC Mayes… - Ecology and society, 2015 - JSTOR
Although most resilience science has focused on individual-level psychosocial factors that
promote individual resilience, theorists and researchers have begun to examine …

The biological effects of childhood trauma

MD De Bellis, A Zisk - Child and Adolescent Psychiatric …, 2014 - childpsych.theclinics.com
The Biological Effects of Childhood Trauma - Child and Adolescent Psychiatric Clinics Skip to
Main Content Skip to Main Menu Advertisement Child and Adolescent Psychiatric Clinics of …

Resilience in development: Progress and transformation

AS Masten, D Cicchetti - Developmental psychopathology: Risk …, 2016 - books.google.com
Resilience science is quintessential developmental psychopathology because it focuses on
variation among individuals in relation to their experiences as they adapt and develop …

Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

I Mahar, FR Bambico, N Mechawar… - … & Biobehavioral Reviews, 2014 - Elsevier
Chronic stressful life events are risk factors for develo** major depression, the
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …