Candida Biofilms: Threats, Challenges, and Promising Strategies

M Cavalheiro, MC Teixeira - Frontiers in medicine, 2018 - frontiersin.org
Candida species are fungal pathogens known for their ability to cause superficial and
systemic infections in the human host. These pathogens are able to persist inside the host …

Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis

C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

The Candida pathogenic species complex

SA Turner, G Butler - Cold Spring Harbor …, 2014 - perspectivesinmedicine.cshlp.org
Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …

The evolution of drug resistance in clinical isolates of Candida albicans

CB Ford, JM Funt, D Abbey, L Issi, C Guiducci… - elife, 2015 - elifesciences.org
Candida albicans is both a member of the healthy human microbiome and a major pathogen
in immunocompromised individuals. Infections are typically treated with azole inhibitors of …

Biofilms and vulvovaginal candidiasis

C Rodríguez-Cerdeira, MC Gregorio… - Colloids and Surfaces B …, 2019 - Elsevier
Candida species, including C. albicans, are part of the mucosal flora of most healthy women,
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …

Fungal biofilms, drug resistance, and recurrent infection

JV Desai, AP Mitchell… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
A biofilm is a surface-associated microbial community. Diverse fungi are capable of biofilm
growth. The significance of this growth form for infection biology is that biofilm formation on …

Virulence factors in Candida species

M Staniszewska - Current Protein and Peptide Science, 2020 - ingentaconnect.com
Fungal diseases are severe and have very high morbidity as well as up to 60% mortality for
patients diagnosed with invasive fungal infection. In this review, in vitro and in vivo studies …

Candida Biofilms: Development, Architecture, and Resistance

J Chandra, PK Mukherjee - Microbial Biofilms, 2015 - Wiley Online Library
The use of indwelling devices in current therapeutic practice is associated with hospital‐
acquired bloodstream and deep tissue infections (1). Transplantation medical procedures …

Portrait of Candida species biofilm regulatory network genes

D Araújo, M Henriques, S Silva - Trends in microbiology, 2017 - cell.com
Most cases of candidiasis have been attributed to Candida albicans, but Candida glabrata,
Candida parapsilosis and Candida tropicalis, designated as non-C. albicans Candida …