Evolution of genetic networks for human creativity

I Zwir, C Del-Val, M Hintsanen, KM Cloninger… - Molecular …, 2022 - nature.com
The genetic basis for the emergence of creativity in modern humans remains a mystery
despite sequencing the genomes of chimpanzees and Neanderthals, our closest hominid …

The complex genetics and biology of human temperament: a review of traditional concepts in relation to new molecular findings

CR Cloninger, KM Cloninger, I Zwir… - Translational …, 2019 - nature.com
Recent genome-wide association studies (GWAS) have shown that temperament is strongly
influenced by more than 700 genes that modulate associative conditioning by molecular …

SynGO: an evidence-based, expert-curated knowledge base for the synapse

F Koopmans, P van Nierop, M Andres-Alonso… - Neuron, 2019 - cell.com
Synapses are fundamental information-processing units of the brain, and synaptic
dysregulation is central to many brain disorders (" synaptopathies"). However, systematic …

[KNJIGA][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Disentangling the personality pathways to well-being

PAS Moreira, RA Inman, CR Cloninger - Scientific Reports, 2023 - nature.com
Recent genomic, psychological, and developmental research shows that human personality
is organized as a complex hierarchy that ascends from individual traits in many specific …

Gene expression networks regulated by human personality

C Del Val, E Díaz de la Guardia-Bolívar, I Zwir… - Molecular …, 2024 - nature.com
Genome-wide association studies of human personality have been carried out, but
transcription of the whole genome has not been studied in relation to personality in humans …

Three genetic–environmental networks for human personality

I Zwir, C Del-Val, J Arnedo, L Pulkki-Råback… - Molecular …, 2021 - nature.com
Phylogenetic, developmental, and brain-imaging studies suggest that human personality is
the integrated expression of three major systems of learning and memory that regulate (1) …

Cultural evolution of genetic heritability

R Uchiyama, R Spicer… - Behavioral and Brain …, 2022 - cambridge.org
Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …

Construct and criterion validity of the HiTOP spectra to predict dimensional and categorical somatization in a large non-western sample

S Komasi, A Hemmati, K Rahmani, F Rezaei - Scientific Reports, 2023 - nature.com
Abstract The Hierarchical Taxonomy of Psychopathology (HiTOP) is a phenotypic data-
driven framework for the classification of psychopathology. We tested the construct and …

Temperament & Character account for brain functional connectivity at rest: A diathesis-stress model of functional dysregulation in psychosis

I Zwir, J Arnedo, A Mesa, C Del Val… - Molecular …, 2023 - nature.com
The human brain's resting-state functional connectivity (rsFC) provides stable trait-like
measures of differences in the perceptual, cognitive, emotional, and social functioning of …