Amyotrophic lateral sclerosis (ALS) is an adult-onset disease which causes the progressive
degeneration of cortical and spinal motoneurons, leading to death a few years after the first …

Background & Aims DJ-1 is universally expressed in various tissues and organs and is
involved in the physiological processes in various liver diseases. However, the role of DJ-1 …

The protein DJ-1 is mutated in rare familial forms of recessive Parkinson's disease and in
parkinsonism accompanied by amyotrophic lateral sclerosis symptoms and dementia. DJ-1 …

The effective storage of lipids in white adipose tissue (WAT) critically impacts whole body
energy homeostasis. Many genes have been implicated in WAT lipid metabolism, including …

Background & aims Transient regeneration–associated steatosis (TRAS) is a process of
temporary hepatic lipid accumulation and is essential for liver regeneration by providing …

Succinylation is a highly conserved post-translational modification that is processed via
enzymatic and non-enzymatic mechanisms. Succinylation exhibits strong effects on protein …

Background Intramuscular fat (IMF) content is a determining factor for meat taste. The
Luchuan pig is a fat-type local breed in southern China that is famous for its desirable meat …

Non-alcoholic steatohepatitis (NASH) is associated with chronic inflammation and gut
bacterial dysbiosis. Studies show that 1-deoxynojirimycin (DNJ) may improve NASH, yet the …

Lecithin cholesterol acyltransferase (LCAT), a crucial enzyme in lipid metabolism, plays
important yet poorly understood roles in tumours, especially in hepatocellular carcinoma …

Sorbic acid (SA) is one of the most commonly used food preservatives worldwide. Despite
SA having no hepatotoxicity at legal dosages, its effect on hepatic lipid metabolism is still …