The promise of organ and tissue preservation to transform medicine
The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …
each year globally and create public health benefits on par with curing cancer. Unmet needs …
The roles of reactive oxygen species and antioxidants in cryopreservation
Cryopreservation has facilitated advancement of biological research by allowing the storage
of cells over prolonged periods of time. While cryopreservation at extremely low …
of cells over prolonged periods of time. While cryopreservation at extremely low …
Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?
Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since
the early history of cryopreservation. It has been used for decades in many thousands of cell …
the early history of cryopreservation. It has been used for decades in many thousands of cell …
Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy
KM Mahadeo, SJ Khazal, H Abdel-Azim… - Nature Reviews …, 2019 - nature.com
In 2017, an autologous chimeric antigen receptor (CAR) T cell therapy indicated for children
and young adults with relapsed and/or refractory CD19+ acute lymphoblastic leukaemia …
and young adults with relapsed and/or refractory CD19+ acute lymphoblastic leukaemia …
The need for novel cryoprotectants and cryopreservation protocols: Insights into the importance of biophysical investigation and cell permeability
Background Cryopreservation is a key method of preservation of biological material for both
medical treatments and conservation of endangered species. In order to avoid cellular …
medical treatments and conservation of endangered species. In order to avoid cellular …
Advanced biomaterials in cell preservation: Hypothermic preservation and cryopreservation
Cell-based medicine has made great advances in clinical diagnosis and therapy for various
refractory diseases, inducing a growing demand for cell preservation as support technology …
refractory diseases, inducing a growing demand for cell preservation as support technology …
Cryopreservation of hematopoietic stem cells: emerging assays, cryoprotectant agents, and technology to improve outcomes
Hematopoietic stem cell (HSC) therapy is widely used to treat a growing number of
hematological and non-hematological diseases. Cryopreservation of HSCs allows for cells …
hematological and non-hematological diseases. Cryopreservation of HSCs allows for cells …
Clinical adoptive regulatory T Cell therapy: State of the art, challenges, and prospective
L Amini, J Kaeda, E Fritsche, A Roemhild… - Frontiers in Cell and …, 2023 - frontiersin.org
Rejection of solid organ transplant and graft versus host disease (GvHD) continue to be
challenging in post transplantation management. The introduction of calcineurin inhibitors …
challenging in post transplantation management. The introduction of calcineurin inhibitors …
[HTML][HTML] Effects of storage media, supplements and cryopreservation methods on quality of stem cells
Despite a vast amount of different methods, protocols and cryoprotective agents (CPA), stem
cells are often frozen using standard protocols that have been optimized for use with cell …
cells are often frozen using standard protocols that have been optimized for use with cell …
Cryopreservation: a comprehensive overview, challenges, and future perspectives
Cryopreservation is the most prevalent method of long‐term cell preservation. Effective cell
cryopreservation depends on freezing, adequate storage, and correct thawing techniques …
cryopreservation depends on freezing, adequate storage, and correct thawing techniques …