[HTML][HTML] Review of NAD (P) H-dependent oxidoreductases: Properties, engineering and application

LS Vidal, CL Kelly, PM Mordaka, JT Heap - Biochimica et Biophysica Acta …, 2018 - Elsevier
Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …

Protein engineering for nicotinamide coenzyme specificity in oxidoreductases: attempts and challenges

AM Chánique, LP Parra - Frontiers in microbiology, 2018 - frontiersin.org
Oxidoreductases are ubiquitous enzymes that catalyze an extensive range of chemical
reactions with great specificity, efficiency, and selectivity. Most oxidoreductases are …

One-pot biocatalytic transformation of adipic acid to 6-aminocaproic acid and 1, 6-hexamethylenediamine using carboxylic acid reductases and transaminases

TP Fedorchuk, AN Khusnutdinova… - Journal of the …, 2019 - ACS Publications
Production of platform chemicals from renewable feedstocks is becoming increasingly
important due to concerns on environmental contamination, climate change, and depletion …

Alanine dehydrogenase and its applications–A review

UC Dave, RK Kadeppagari - Critical reviews in biotechnology, 2019 - Taylor & Francis
Abstract Alanine dehydrogenase (AlaDH)(EC 1.4. 1.1) is a microbial enzyme that catalyzes
a reversible conversion of L-alanine to pyruvate. Inter-conversion of alanine and pyruvate by …

Scalable, two‐stage, autoinduction of recombinant protein expression in E. coli utilizing phosphate depletion

R Menacho‐Melgar, Z Ye, EA Moreb… - Biotechnology and …, 2020 - Wiley Online Library
We report the scalable production of recombinant proteins in Escherichia coli, reliant on
tightly controlled autoinduction, triggered by phosphate depletion in the stationary phase …

De novo biosynthesis of nylon 12 monomer ω-aminododecanoic acid

J Ge, T Wang, H Yu, L Ye - Nature Communications, 2025 - nature.com
Nylon 12 is valued for its exceptional properties and diverse industrial applications.
Traditional chemical synthesis of nylon 12 faces significant technical challenges and …

Alanine dehydrogenases from four different microorganisms: Characterization and their application in L-alanine production

P Gu, Q Ma, S Zhao, Q Li, J Gao - Biotechnology for Biofuels and …, 2023 - Springer
Abstract Background Alanine dehydrogenase (AlaDH) belongs to oxidoreductases, and it
exists in several different bacteria species and plays a key role in microbial carbon and …

Two-stage dynamic deregulation of metabolism improves process robustness & scalability in engineered E. coli.

Z Ye, S Li, JN Hennigan, J Lebeau, EA Moreb… - Metabolic …, 2021 - Elsevier
We report that two-stage dynamic control improves bioprocess robustness as a result of the
dynamic deregulation of central metabolism. Dynamic control is implemented during …

Optimizing Hexose Utilization Pathways of Cupriavidus necator for Improving Growth and L-Alanine Production under Heterotrophic and Autotrophic Conditions

L Wang, H Luo, B Yao, J Yao, J Zhang - International Journal of …, 2023 - mdpi.com
Cupriavidus necator is a versatile microbial chassis to produce high-value products.
Blocking the poly-β-hydroxybutyrate synthesis pathway (encoded by the phaC1AB1 operon) …

Construction of an alanine dehydrogenase gene deletion strain for vaccine development against nocardia seriolae in hybrid snakehead (Channa maculata♀× …

Y Liu, T Weng, X Pan, Y Wen, H Yang, J Chen… - Fish & Shellfish …, 2023 - Elsevier
Nocardia seriolae is the main pathogen of fish nocardiosis. In our previous study, alanine
dehydrogenase was identified as a potential virulence factor of N. seriolae. On the basis of …