Sympathetic nervous system overactivity and its role in the development of cardiovascular disease

SC Malpas - Physiological reviews, 2010 - journals.physiology.org
This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

The paraventricular nucleus of the hypothalamus in control of blood pressure and blood pressure variability

B Savić, D Murphy, N Japundžić-Žigon - Frontiers in Physiology, 2022 - frontiersin.org
The paraventricular nucleus (PVN) is a highly organized structure of the hypothalamus that
has a key role in regulating cardiovascular and osmotic homeostasis. Functionally, the PVN …

Maintenance of beta-cell function and survival following islet isolation requires re-establishment of the islet-matrix relationship

RN Wang, L Rosenberg - Journal of Endocrinology, 1999 - joe.bioscientifica.com
Obesity is associated with insulin resistance and type 2 diabetes; molecular mechanisms
that promote energy expenditure can be utilized for effective therapy. Src-associated in …

Identification of branching paraventricular neurons of the hypothalamus that project to the rostroventrolateral medulla and spinal cord

S Pyner, JH Coote - Neuroscience, 2000 - Elsevier
The paraventricular nucleus of the hypothalamus has efferent connections to autonomic
nuclei known to ultimately regulate cardiovascular function. Studies have revealed …

Neurochemistry of the paraventricular nucleus of the hypothalamus: implications for cardiovascular regulation

S Pyner - Journal of chemical neuroanatomy, 2009 - Elsevier
The paraventricular nucleus of the hypothalamus (PVN) is an important site for autonomic
and endocrine homeostasis. The PVN integrates specific afferent stimuli to produce an …

Modulation of cardiovascular control mechanisms and their interaction

PB Persson - Physiological reviews, 1996 - journals.physiology.org
It is generally held that the role of a specific control element can only be understood within
its physiological environment. The reviewed studies make it clear that there is a potent …

Transneuronal labeling of CNS neuropeptide and monoamine neurons after pseudorabies virus injections into the stellate ganglion

ASP Jansen, MW Wessendorf, AD Loewy - Brain research, 1995 - Elsevier
The viral transneuronal labeling method was used in combination with
immunohistochemical procedures to identify CNS neuropeptide and monoamine neurons …

The rhythmicity of sympathetic nerve activity

SC Malpas - Progress in neurobiology, 1998 - Elsevier
This review focuses on that most engaging feature of the sympathetic nervous system, its
rhythmicity. In particular examining the nature of sympathetic nerve activity (SNA), its …

Electrophysiological and morphological properties of pre‐autonomic neurones in the rat hypothalamic paraventricular nucleus

JE Stern - The Journal of physiology, 2001 - Wiley Online Library
1 The cellular properties of pre‐autonomic neurones in the hypothalamic paraventricular
nucleus (PVN) were characterized by combining in vivo retrograde tracing techniques, in …

The paraventricular nucleus of the hypothalamus sends efferents to the spinal cord of the rat that closely appose sympathetic preganglionic neurones projecting to the …

RN Ranson, K Motawei, S Pyner, JH Coote - Experimental brain research, 1998 - Springer
Using a combination of anterograde and retrograde neuronal tract-tracing techniques, the
descending projections from the paraventricular nucleus of the hypothalamus (PVN) to the …