Apoptotic cell death in disease—Current understanding of the NCCD 2023

I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

[HTML][HTML] An update on the role of Hippo signaling pathway in ischemia-associated central nervous system diseases

X Wei, G Huang, J Liu, J Ge, W Zhang, Z Mei - Biomedicine & …, 2023 - Elsevier
The most frequent reason of morbidity and mortality in the world, cerebral ischemia sets off a
chain of molecular and cellular pathologies that associated with some central nervous …

Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases

W Balestri, R Sharma, VA da Silva, BC Bobotis… - Journal of …, 2024 - Springer
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

[HTML][HTML] Integrating the roles of midbrain dopamine circuits in behavior and neuropsychiatric disease

APF Chen, L Chen, TA Kim, Q **ong - Biomedicines, 2021 - mdpi.com
Dopamine (DA) is a behaviorally and clinically diverse neuromodulator that controls CNS
function. DA plays major roles in many behaviors including locomotion, learning, habit …

Perfluorooctane sulfonates induces neurobehavioral changes and increases dopamine neurotransmitter levels in zebrafish larvae

L Wu, Y Dang, LX Liang, YC Gong, M Zeeshan, Z Qian… - Chemosphere, 2022 - Elsevier
It has been reported that exposure to perfluorooctane sulfonates (PFOS) causes behavioral
abnormalities in zebrafish larvae, but the possible mechanisms underlying these changes …

Neuronal guidance genes in health and diseases

J Yuasa-Kawada, M Kinoshita-Kawada, Y Tsuboi… - Protein & …, 2023 - academic.oup.com
Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …

A systematic review of genome-wide association studies for pain, nociception, neuropathy, and pain treatment responses

S Li, A Brimmers, RLM van Boekel, KCP Vissers… - Pain, 2023 - journals.lww.com
Pain is the leading cause of disability worldwide, imposing an enormous burden on
personal health and society. Pain is a multifactorial and multidimensional problem …

Standpoints in mitochondrial dysfunction: Underlying mechanisms in search of therapeutic strategies

LA Videla, A Marimán, B Ramos, MJ Silva… - Mitochondrion, 2022 - Elsevier
Mitochondrial dysfunction has been defined as a reduced efficiency of mitochondria to
produce ATP given by a loss of mitochondrial membrane potential, alterations in the electron …

Mitochondrial dysfunction as a target in spinal cord injury: intimate correlation between pathological processes and therapeutic approaches

J Schmidt, HR Quintá - Neural regeneration research, 2023 - journals.lww.com
Traumatic spinal cord injuries interrupt the connection of all axonal projections with their
neuronal targets below and above the lesion site. This interruption results in either …

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

M Cai, Q Zheng, Y Chen, S Liu, H Zhu… - Frontiers in Molecular …, 2024 - frontiersin.org
Netrin-1 was initially discovered as a neuronal growth cue for axonal guidance, and its
functions have later been identified in inflammation, tumorigenesis, neurodegeneration, and …