Computational network biology: data, models, and applications

C Liu, Y Ma, J Zhao, R Nussinov, YC Zhang, F Cheng… - Physics Reports, 2020 - Elsevier
Biological entities are involved in intricate and complex interactions, in which uncovering the
biological information from the network concepts are of great significance. Benefiting from …

Better safe than sorry: A common signature of general vulnerability for psychopathology

O Van den Bergh, J Brosschot… - Perspectives on …, 2021 - journals.sagepub.com
Several labels, such as neuroticism, negative emotionality, and dispositional negativity,
indicate a broad dimension of psychopathology. However, largely separate, often disorder …

Combined effects of neuroticism and negative emotional context on spontaneous EEG dynamics

M Deodato, M Seeber, K Mammeri… - Social Cognitive and …, 2024 - academic.oup.com
Neuroticism is a personality trait with great clinical relevance, defined as a tendency to
experience negative affect, sustained self-generated negative thoughts and impaired …

Interactions between personality, depression, anxiety and cognition to understand early stage of Alzheimer's disease

V Zufferey, A Gunten, F Kherif - Current topics in medicinal …, 2020 - ingentaconnect.com
The multifaceted nature of Alzheimer's disease (AD) and Mild cognitive impairment (MCI)
can lead to wide inter-individual differences in disease manifestation in terms of brain …

Statistical perspective on functional and causal neural connectomics: The Time-Aware PC algorithm

R Biswas, E Shlizerman - PLOS Computational Biology, 2022 - journals.plos.org
The representation of the flow of information between neurons in the brain based on their
activity is termed the causal functional connectome. Such representation incorporates the …

[HTML][HTML] The individualized prediction of cognitive test scores in mild cognitive impairment using structural and functional connectivity features

J Yu, I Rawtaer, J Fam, L Feng, EH Kua, R Mahendran - NeuroImage, 2020 - Elsevier
Neuropsychological assessments are essential in diagnosing age-related neurocognitive
disorders. However, they are lengthy in duration and can be unreliable at times. To this end …

Intrinsic functional connectomes characterize neuroticism in major depressive disorder and predict antidepressant treatment outcomes

TA Braund, IA Breukelaar, K Griffiths, G Tillman… - Biological Psychiatry …, 2022 - Elsevier
Background Antidepressant efficacy in people with major depressive disorder remains
modest, yet identifying treatment-predictive neurobiological markers may improve outcomes …

Neuroticism polygenic risk predicts conversion from mild cognitive impairment to Alzheimer's disease by impairing inferior parietal surface area

Q Li, X Lv, Q Qian, K Liao, X Du… - Human Brain …, 2024 - Wiley Online Library
The high prevalence of conversion from amnestic mild cognitive impairment (aMCI) to
Alzheimer's disease (AD) makes early prevention of AD extremely critical. Neuroticism, a …

Neuroticism vulnerability factors of anxiety symptoms in adolescents and early adults: an analysis using the bi-factor model and multi-wave longitudinal model

Y He, A Li, K Li, J **ao - PeerJ, 2021 - peerj.com
Background Neuroticism and stress are important vulnerability factors in the development
and outcome of anxiety symptoms. However, as neuroticism is a heterogeneity trait, it is still …

[HTML][HTML] Multi-scale hierarchical brain regions detect individual and interspecies variations of structural connectivity in macaque monkeys and humans

K Ouchi, D Yoshimaru, A Takemura, S Yamamoto… - NeuroImage, 2024 - Elsevier
Macaques are representative animal models in translational research. However, the distinct
shape and location of the brain regions between macaques and humans prevents us from …