PharmVar Tutorial on CYP2D6 Structural Variation Testing and Recommendations on Reporting
AJ Turner, C Nofziger, BE Ramey, RC Ly… - Clinical …, 2023 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly
polymorphic human CYP2D6 gene locus and a comprehensive summary of structural …
polymorphic human CYP2D6 gene locus and a comprehensive summary of structural …
The emergence, implementation, and future growth of pharmacogenomics in psychiatry: a narrative review
Psychotropic medication efficacy and tolerability are critical treatment issues faced by
individuals with psychiatric disorders and their healthcare providers. For some people, it can …
individuals with psychiatric disorders and their healthcare providers. For some people, it can …
Cost-effectiveness of pharmacogenomic-guided treatment for major depression
S Ghanbarian, GWK Wong, M Bunka, L Edwards… - Cmaj, 2023 - Can Med Assoc
Background: Pharmacogenomic testing to identify variations in genes that influence
metabolism of antidepressant medications can enhance efficacy and reduce adverse effects …
metabolism of antidepressant medications can enhance efficacy and reduce adverse effects …
Metabolic characterization of the new benzimidazole synthetic opioids-nitazenes
The recent re-emergence and the increasing popularity of nitazenes, a group of new
synthetic opioids (NSO) that belong to the benzimidazole chemical class, has raised public …
synthetic opioids (NSO) that belong to the benzimidazole chemical class, has raised public …
Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
Cytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for
antidepressant metabolism and polymorphisms of these genes have been determined to …
antidepressant metabolism and polymorphisms of these genes have been determined to …
Escitalopram and sertraline population pharmacokinetic analysis in pediatric patients
Abstract Background and Objective Escitalopram and sertraline are commonly prescribed
for anxiety and depressive disorders in children and adolescents. The pharmacokinetics …
for anxiety and depressive disorders in children and adolescents. The pharmacokinetics …
[HTML][HTML] Safety analysis of co-administering tacrolimus and omeprazole in renal transplant recipients–A review
M Miedziaszczyk, I Idasiak-Piechocka - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Tacrolimus is a calcineurin inhibitor used to prevent rejection in allogenic solid organ
transplant recipients, which is metabolized in the liver with cytochrome P450 isoforms 3A4 …
transplant recipients, which is metabolized in the liver with cytochrome P450 isoforms 3A4 …
An updated examination of the perception of barriers for pharmacogenomics implementation and the usefulness of drug/gene pairs in Latin America and the …
A Salas-Hernández, M Galleguillos… - Frontiers in …, 2023 - frontiersin.org
Pharmacogenomics (PGx) is considered an emergent field in develo** countries.
Research on PGx in the Latin American and the Caribbean (LAC) region remains scarce …
Research on PGx in the Latin American and the Caribbean (LAC) region remains scarce …
The effects of CYP2C19 genotype on proxies of SSRI antidepressant response in the UK biobank
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly used
psychopharmaceutical treatment for major depressive disorder (MDD), but individual …
psychopharmaceutical treatment for major depressive disorder (MDD), but individual …
Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity
P Zubiaur, P Soria‐Chacartegui… - Clinical …, 2023 - Wiley Online Library
A novel haplotype composed of two non‐coding variants, CYP2C18 NM_000772. 3: c.* 31T
(rs2860840) and NM_000772. 2: c. 819+ 2182G (rs11188059), referred to as “CYP2C: TG,” …
(rs2860840) and NM_000772. 2: c. 819+ 2182G (rs11188059), referred to as “CYP2C: TG,” …