A radiologist's guide to the 2021 WHO Central Nervous System Tumor Classification: part I—key concepts and the spectrum of diffuse gliomas

DR Johnson, C Giannini, RA Vaubel, JM Morris… - Radiology, 2022 - pubs.rsna.org
The fifth edition of the World Health Organization (WHO) classification of tumors of the
central nervous system, published in 2021, contains substantial updates in the classification …

[HTML][HTML] Paediatric-type diffuse high-grade gliomas in the 5th CNS WHO Classification

F Gianno, I Giovannoni, B Cafferata… - Pathologica, 2022 - ncbi.nlm.nih.gov
As a relevant element of novelty, the fifth CNS WHO Classification highlights the distinctive
pathobiology underlying gliomas arising primarily in children by recognizing for the first time …

Major changes in 2021 world health organization classification of central nervous system tumors

R Kurokawa, M Kurokawa, A Baba, Y Ota… - Radiographics, 2022 - pubs.rsna.org
The World Health Organization (WHO) published the fifth edition of the WHO Classification
of Tumors of the Central Nervous System (WHO CNS5) in 2021, as an update of the WHO …

The 2021 WHO Classification for Gliomas and Implications on Imaging Diagnosis: Part 2—Summary of Imaging Findings on Pediatric‐Type Diffuse High‐Grade …

YW Park, P Vollmuth, M Foltyn‐Dumitru… - Journal of Magnetic …, 2023 - Wiley Online Library
The fifth edition of the World Health Organization (WHO) classification of central nervous
system tumors published in 2021 advances the role of molecular diagnostics in the …

Recapitulating the key advances in the diagnosis and prognosis of high-grade gliomas: second half of 2021 update

G Frosina - International Journal of Molecular Sciences, 2023 - mdpi.com
High-grade gliomas (World Health Organization grades III and IV) are the most frequent and
fatal brain tumors, with median overall survivals of 24–72 and 14–16 months, respectively …

Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review

A Lasocki, G Abdalla, G Chow, SC Thust - Cancer Imaging, 2022 - Springer
Background Advances in molecular diagnostics accomplished the discovery of two
malignant glioma entities harboring alterations in the H3 histone: diffuse midline glioma, H3 …

H3G34-mutant gliomas—a review of molecular pathogenesis and therapeutic options

AV Nguyen, JM Soto, SM Gonzalez, J Murillo… - Biomedicines, 2023 - mdpi.com
The 2021 World Health Organization Classification of Tumors of the Central Nervous System
reflected advances in understanding of the roles of oncohistones in gliomagenesis with the …

Systematic review of diffuse hemispheric glioma, H3 G34-mutant: Outcomes and associated clinical factors

C Crowell, D Mata-Mbemba, J Bennett… - Neuro-Oncology …, 2022 - academic.oup.com
Background A comprehensive review and description of the clinical features that impact
prognosis for patients with diffuse hemispheric glioma, H3 G34-mutant (G34-DHG) is …

Brain tumor imaging in adolescents and young adults: 2021 WHO updates for molecular-based tumor types

MW Wagner, P Jabehdar Maralani, J Bennett, L Nobre… - Radiology, 2024 - pubs.rsna.org
Published in 2021, the fifth edition of the World Health Organization (WHO) classification of
tumors of the central nervous system (CNS) introduced new molecular criteria for tumor …

Newly recognized CNS tumors in the 2021 World Health Organization Classification: Imaging overview with histopathologic and genetic correlation

RK Rigsby, P Brahmbhatt, AB Desai… - American Journal …, 2023 - Am Soc Neuroradiology
In 2021, the World Health Organization released an updated classification of CNS tumors.
This update reflects the growing understanding of the importance of genetic alterations …