Background Therapeutic hypothermia (TH) is regarded as the most efficacious therapy for
neonatal hypoxic encephalopathy. However, limitations in previous systematic reviews and …

Background Although therapeutic hypothermia reduces death or disability after neonatal
encephalopathy in high-income countries, its safety and efficacy in low-income and middle …

Methods We included full articles and book chapters published in English on PubMed with
references to “hypoxic ischemic encephalopathy”,“birth asphyxia”,“therapeutic hypothermia” …

Importance The association between place of birth and hypothermic neuroprotection after
hypoxic-ischemic encephalopathy (HIE) in low-and middle-income countries (LMICs) is …

Importance There are wide disparities in neonatal mortality rates (NMRs, deaths< 28 days of
life after live birth per 1000 live births) between countries in Europe, indicating potential for …

Hypoxic ischaemic encephalopathy (HIE) is a major cause of neonatal mortality and
disability in the United Kingdom (UK) and has significant human and financial costs …

Introduction Perinatal asphyxia (PA) still causes significant morbidity and mortality.
Therapeutic hypothermia (TH) is the only effective therapy for neonates with moderate to …

Abstract Sub-Saharan Africa (SSA) has the highest burden of neonatal hypoxic ischemic
encephalopathy (HIE) in the world. However, there are few descriptions of HIE management …

In the past decade, therapeutic hypothermia using a variety of low-cost devices has been
widely implemented in India and other low-and middle-income countries (LMIC) without …

Hypoxic-ischemic syndrome (HIS) and Hypoxic-ischemic encephalopathy (HIE) are
conditions that affect term and premature babies, with different pathophysiology and different …