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Peripheral neuropathy in mouse models of diabetes
CG Jolivalt, KE Frizzi, L Guernsey… - Current protocols in …, 2016 - Wiley Online Library
Peripheral neuropathy is a frequent complication of chronic diabetes that most commonly
presents as a distal degenerative polyneuropathy with sensory loss. Around 20% to 30% of …
presents as a distal degenerative polyneuropathy with sensory loss. Around 20% to 30% of …
Methods for evaluating gait associated dynamic balance and coordination in rodents
AD Modi, A Parekh, ZH Patel - Behavioural Brain Research, 2024 - Elsevier
Balance is the dynamic and unconscious control of the body's centre of mass to maintain
postural equilibrium. Regulated by the vestibular system, head movement and acceleration …
postural equilibrium. Regulated by the vestibular system, head movement and acceleration …
Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function
The risk for neurodegenerative diseases increases with aging, with various pathological
conditions and functional deficits accompanying these diseases. We have previously …
conditions and functional deficits accompanying these diseases. We have previously …
Innate immunity activation in the early brain injury period following subarachnoid hemorrhage
T Gris, P Laplante, P Thebault, R Cayrol… - Journal of …, 2019 - Springer
Background Aneurysmal subarachnoid hemorrhage (SAH) is a catastrophic disease with
devastating consequences, including a high mortality rate and severe disabilities among …
devastating consequences, including a high mortality rate and severe disabilities among …
Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR
Z Hao, L Liu, Z Tao, R Wang, H Ren, H Sun… - Nature …, 2019 - nature.com
A GGGGCC hexanucleotide repeat expansion in intron 1 of chromosome 9 open reading
frame 72 (C9ORF72) gene is the most common genetic cause of amyotrophic lateral …
frame 72 (C9ORF72) gene is the most common genetic cause of amyotrophic lateral …
Subcutaneous rotenone rat model of Parkinson's disease: Dose exploration study
ZN Zhang, JS Zhang, J **ang, ZH Yu, W Zhang, M Cai… - Brain research, 2017 - Elsevier
Subcutaneous administration of rotenone has recently attracted attention because of its
convenience, simplicity and efficacy in replicating features of Parkinson's disease (PD) in …
convenience, simplicity and efficacy in replicating features of Parkinson's disease (PD) in …
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
TG McWilliams, E Barini… - Royal Society …, 2018 - royalsocietypublishing.org
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell
culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and …
culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and …
Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice
Neurodegenerative diseases associated with old age such as Alzheimer's disease present
major problems for society, and they currently have no cure. The telomere protective caps at …
major problems for society, and they currently have no cure. The telomere protective caps at …
Analysis of motor function in the Tg4-42 mouse model of Alzheimer's disease
JM Wagner, ME Sichler, EM Schleicher… - Frontiers in behavioral …, 2019 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder and the most common form of
dementia. Hallmarks of AD are memory impairments and cognitive deficits, but non-cognitive …
dementia. Hallmarks of AD are memory impairments and cognitive deficits, but non-cognitive …
Enriched environment decreases microglia and brain macrophages inflammatory phenotypes through adiponectin-dependent mechanisms: Relevance to depressive …
J Chabry, S Nicolas, J Cazareth, E Murris… - Brain, behavior, and …, 2015 - Elsevier
Regulation of neuroinflammation by glial cells plays a major role in the pathophysiology of
major depression. While astrocyte involvement has been well described, the role of …
major depression. While astrocyte involvement has been well described, the role of …