Prediction error signaling explains neuronal mismatch responses in the medial prefrontal cortex

L Casado-Román, GV Carbajal, D Pérez-González… - PLoS …, 2020‏ - journals.plos.org
The mismatch negativity (MMN) is a key biomarker of automatic deviance detection thought
to emerge from 2 cortical sources. First, the auditory cortex (AC) encodes spectral …

Modelling mouse auditory response dynamics along a continuum of consciousness using a deep recurrent neural network

JA O'Reilly - Journal of Neural Engineering, 2022‏ - iopscience.iop.org
Objective. Understanding neurophysiological changes that accompany transitions between
anaesthetized and conscious states is a key objective of anesthesiology and consciousness …

Decoding violated sensory expectations from the auditory cortex of anaesthetised mice: Hierarchical recurrent neural network depicts separate 'danger'and 'safety' …

JA O'Reilly, T Angsuwatanakul… - European Journal of …, 2022‏ - Wiley Online Library
The ability to respond appropriately to sensory information received from the external
environment is among the most fundamental capabilities of central nervous systems. In the …

Classical and controlled auditory mismatch responses to multiple physical deviances in anaesthetised and conscious mice

JA O'Reilly, BA Conway - European Journal of Neuroscience, 2021‏ - Wiley Online Library
Human mismatch negativity (MMN) is modelled in rodents and other non‐human species to
examine its underlying neurological mechanisms, primarily described in terms of deviance …

Auditory evoked-potential abnormalities in a mouse model of 22q11. 2 Deletion Syndrome and their interactions with hearing impairment

C Lu, JF Linden - Translational Psychiatry, 2025‏ - nature.com
Abstract The 22q11. 2 deletion is a risk factor for multiple psychiatric disorders including
schizophrenia and also increases vulnerability to middle-ear problems that can cause …

[HTML][HTML] Roving oddball paradigm elicits sensory gating, frequency sensitivity, and long-latency response in common marmosets

JA O'Reilly - IBRO Neuroscience Reports, 2021‏ - Elsevier
Mismatch negativity (MMN) is a candidate biomarker for neuropsychiatric disease.
Understanding the extent to which it reflects cognitive deviance-detection or purely sensory …

Auditory evoked-potential abnormalities in a mouse model of 22q11. 2 Deletion Syndrome and their interactions with hearing impairment

C Lu, JF Linden - bioRxiv, 2023‏ - biorxiv.org
Abstract Background The 22q11. 2 chromosomal microdeletion is one of the strongest
known genetic risk factors for schizophrenia;∼ 30% of carriers develop schizophrenia in …

More evidence for a long-latency mismatch response in urethane-anaesthetised mice

JA O'Reilly, T Angsuwatanakul - Hearing Research, 2021‏ - Elsevier
Long-latency mismatch responses to oddball stimuli have recently been observed from
anaesthetised rodents. This electrophysiological activity is viewed through 200 to 700 ms …

Blind source separation of event-related potentials using a recurrent neural network

JA O'Reilly, H Sunthornwiriya-Amon, N Aparprasith… - …, 2024‏ - pmc.ncbi.nlm.nih.gov
Event-related potentials (ERPs) are a superposition of electric potential differences
generated by neurophysiological activity associated with psychophysical events …

Mismatch Negativity (MMN) as a Pharmacodynamic/Response Biomarker for NMDA Receptor and Excitatory/Inhibitory Imbalance-Targeted Treatments in …

DC Javitt - … in Neuropsychiatric Disorders: Etiologic and Treatment …, 2024‏ - Springer
Schizophrenia is a major mental disorder that affects approximately 0.5% of the population
worldwide. Persistent negative symptoms and cognitive impairments associated with …