Genome-wide association studies (GWASs) have identified several susceptibility loci for
bipolar disorder (BD) and shown that the genetic architecture of BD can be explained by …

Although large-scale genome-wide association studies (GWAS) have identified an
association between MAD1L1 (Mitotic Arrest Deficient-1 Like 1) and the pathology of …

Variable number tandem repeat (VNTR) is a pervasive and highly mutable genetic feature
that varies in both length and repeat sequence. Despite the well-studied copy-number …

Bipolar disorder (BD) is a heritable psychiatric disorder with a complex etiology that is often
associated with cortical alterations. Morphometric studies in adults with BD are well …

Abstract Mitotic arrest deficient-like-1 (MAD2, also known as MAD2L1) is thought to be an
important spindle assembly checkpoint protein, which ensures accurate chromosome …

Background: The genetic etiology of fetal chromosome abnormalities remains unknown,
which brings about an enormous burden for patients, families, and society. The spindle …

Presently, 151 widely-diverse pyridinylimidazole-based compounds that show inhibitory
activities at the TNF-α release were investigated. By using the distance comparison …

MAD1L1 is coiled-coil protein that binds to improperly attached kinetochrore, what results in
recruitment and interaction with MAD2L1, activation of the mitotic checkpoint complex …

Los esfingolípidos tienen un papel importante en las vías de transducción de señales que
regulan tanto funciones fisiológicas como respuestas a estrés en eucariontes. En plantas …