The role of P450 enzymes in malaria and other vector‐borne infectious diseases

O Skorokhod, E Vostokova, G Gilardi - BioFactors, 2024 - Wiley Online Library
Vector‐borne infectious diseases are still an important global health problem. Malaria is the
most important among them, mainly pediatric, life‐threatening disease. Malaria and other …

[HTML][HTML] Evolutionary consequences of long-distance dispersal in mosquitoes

TL Schmidt - Current Opinion in Insect Science, 2024 - Elsevier
Highlights•Long-distance dispersal underlies the global threat of mosquito disease•Long-
distance dispersal and active flight should be analysed as distinct processes•Insecticide …

Discovery of Knock‐Down Resistance in the Major African Malaria Vector Anopheles funestus

JO Odero, TPW Dennis, B Polo, J Nwezeobi… - Molecular …, 2024 - Wiley Online Library
ABSTRACT A major insecticide resistance mechanism in insect pests is knock‐down
resistance (kdr) caused by mutations in the voltage‐gated sodium channel (Vgsc) gene …

Genetic markers associated with the widespread insecticide resistance in malaria vector Anopheles funestus populations across Tanzania

JO Odero, IH Nambunga, JP Masalu, G Mkandawile… - Parasites & …, 2024 - Springer
Background Anopheles funestus is a leading vector of malaria in most parts of East and
Southern Africa, yet its ecology and responses to vector control remain poorly understood …

Parallel Evolution in Mosquito Vectors—A Duplicated Esterase Locus is Associated With Resistance to Pirimiphos-methyl in Anopheles gambiae

SC Nagi, ER Lucas, A Egyir-Yawson… - Molecular Biology …, 2024 - academic.oup.com
The primary control methods for the African malaria mosquito, Anopheles gambiae, are
based on insecticidal interventions. Emerging resistance to these compounds is therefore of …

Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

TPW Dennis, P Pescod, S Barasa, LT Cerdeira… - Scientific Reports, 2024 - nature.com
Abstract The Democratic Republic of Congo (DRC) suffers from one of the highest malaria
burdens worldwide, but information on its Anopheles vector populations is relatively limited …

Genome-wide association studies unveil major genetic loci driving insecticide resistance in Anopheles funestus in four eco-geographical settings across Cameroon

M Gadji, JA Kengne-Ouafo, M Tchouakui, MJ Wondji… - BMC genomics, 2024 - Springer
Background Insecticide resistance is jeopardising malaria control efforts in Africa.
Deciphering the evolutionary dynamics of mosquito populations country-wide is essential for …

Ecological risks caused by neonicotinoid pesticides in sediments: A case study of freshwater basins in China

X Chen, P Wen, Y Sun, P Ding, H Chen, H Li… - Science of The Total …, 2024 - Elsevier
Neonicotinoid insecticides (NNIs) are extensively used in agricultural production in China
due to their selective neurotoxicity towards target insects. In recent years, the rapid …

Copy number variants underlie major selective sweeps in insecticide resistance genes in Anopheles arabiensis

ER Lucas, SC Nagi, B Kabula, B Batengana… - PLoS …, 2024 - journals.plos.org
To keep ahead of the evolution of resistance to insecticides in mosquitoes, national malaria
control programmes must make use of a range of insecticides, both old and new, while …

[HTML][HTML] Widespread occurrence of copy number variants and fixation of pyrethroid target site resistance in Anopheles gambiae (sl) from southern Côte d'Ivoire

RMA Kouamé, A Lynd, JKI Kouamé, L Vavassori… - Current research in …, 2023 - Elsevier
Resistance to pyrethroid and organophosphate insecticides in the malaria vector Anopheles
gambiae (sl) is conferred by a variety of genetic mutations, including single nucleotide …