[PDF][PDF] Fibromyalgia: one year in review 2022

V Giorgi, S Sirotti, ME Romano, D Marotto… - Clin Exp …, 2022 - clinexprheumatol.org
Fibromyalgia syndrome (FM) is a chronic widespread pain syndrome characterised by
fatigue, sleep disturbances and many idiopathic pain symptoms. The aim of this review is to …

Mechanisms underlying paclitaxel-induced neuropathic pain: Channels, inflammation and immune regulations

Y Xu, Z Jiang, X Chen - European journal of pharmacology, 2022 - Elsevier
Paclitaxel is a chemotherapeutic agent widely used for many types of malignancies.
However, when paclitaxel is used to treat tumors, patients commonly experience severe …

Inflammation, autoimmunity, and infection in fibromyalgia: a narrative review

M Paroli, C Gioia, D Accapezzato… - International Journal of …, 2024 - mdpi.com
Fibromyalgia (FM) is a chronic disease characterized by widespread musculoskeletal pain
of unknown etiology. The condition is commonly associated with other symptoms, including …

Microglia polarization in nociplastic pain: mechanisms and perspectives

AA Atta, WW Ibrahim, AF Mohamed… - …, 2023 - Springer
Nociplastic pain is the third classification of pain as described by the International
Association for the Study of Pain (IASP), in addition to the neuropathic and nociceptive pain …

Potential role of blood biomarkers in patients with fibromyalgia: a systematic review with meta-analysis

D Kumbhare, S Hassan, D Diep, FCK Duarte, J Hung… - Pain, 2022 - journals.lww.com
Fibromyalgia (FM) is a complex chronic pain condition. Its symptoms are nonspecific, and to
date, no objective test exists to confirm FM diagnosis. Potential objective measures include …

[HTML][HTML] High-dose vitamin B6 (pyridoxine) displays strong anti-inflammatory properties in lipopolysaccharide-stimulated monocytes

K Mikkelsen, N Dargahi, S Fraser, V Apostolopoulos - Biomedicines, 2023 - mdpi.com
Vitamin B6 is shown to have anti-inflammatory properties, which makes it an interesting
nutraceutical agent. Vitamin B6 deficiency is well established as a contributor to …

[HTML][HTML] Astaxanthin alleviates fibromyalgia pain and depression via NLRP3 inflammasome inhibition

L Zhao, X Tao, K Wang, Y Song, B Zhang… - Biomedicine & …, 2024 - Elsevier
Fibromyalgia is characterised by widespread chronic pain and is often accompanied by
comorbidities such as sleep disorders, anxiety, and depression. Because it is often …

High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology

JA Tierney, CD Uong, ME Lenert, M Williams… - Scientific reports, 2022 - nature.com
Understanding the interactions between diet, obesity, and diabetes is important to tease out
mechanisms in painful pathology. Western diet is rich in fats, producing high amounts of …

[HTML][HTML] Influence of routine exercise on the peripheral immune system to prevent and alleviate pain

JB Lesnak, G Berardi, KA Sluka - Neurobiology of Pain, 2023 - Elsevier
Routine physical activity reduces the onset of pain and exercise is a first line treatment for
individuals who develop chronic pain. In both preclinical and clinical research regular …

Assessing causal relationship between circulating cytokines and age-related neurodegenerative diseases: a bidirectional two-sample Mendelian randomization …

Z Yin, J Chen, M **a, X Zhang, Y Li, Z Chen, Q Bao… - Scientific reports, 2023 - nature.com
Numerous studies have reported that circulating cytokines (CCs) are linked to age-related
neurodegenerative diseases (ANDDs); however, there is a lack of systematic investigation …