Systemic sclerosis (SSc) is an autoimmune disease characterized by immune dysfunction,
vascular system dysfunction, and tissue fibrosis. Vascular injury, vascular remodeling, and …

Nanomedicine is currently showing great promise for new methods of diagnosing and
treating many diseases, particularly in kidney disease and transplantation. The unique …

The chronic rejection responses and side effects of the systematic administration of
immunosuppressants are the main obstacles to heart allograft and patient survival. The …

The lymph node (LN) is the primary site of alloimmunity activation and regulation during
transplantation. Here, we investigated how fibroblastic reticular cells (FRCs) facilitate the …

The immune system maintains homeostasis and protects the body from pathogens, mutated
cells, and other harmful substances. When immune homeostasis is disrupted, excessive …

Innovative approaches in nanoparticle design have facilitated the creation of new
formulations of nanoparticles that are capable of selectively calibrating the immune …

Systemic immunosuppression for the mitigation of immune rejection after organ
transplantation causes adverse side effects and constrains the long-term benefits of the …

Targeted delivery of therapeutics through the use of nanoparticles (NPs) has emerged as a
promising method that increases their efficacy and reduces their side effects. NPs can be …

Due to higher vulnerability and immunogenicity of extended criteria donor (ECD) organs
used for organ transplantation (Tx), the discovery of new treatment strategies, involving …

Introduction Cell transplantation is a promising curative therapeutic strategy whereby
impaired organ function can be restored without the need for whole-organ transplantation. A …