Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …

Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …

In recent years, microRNAs (miRNAs) have been identified as mediators of tumour
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …

To protect tissues and the organism from disease, potentially harmful cells are removed
through programmed cell death processes, including apoptosis and necroptosis. These …

MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …

MicroRNAs (miRNAs) mainly function as post-transcriptional regulators and are involved in
a wide range of physiological and pathophysiological processes such as cell proliferation …

Aetiology of intervertebral disc degeneration (IDD) is complex, with genetic, developmental,
biochemical and biomechanical factors contributing to the disease process. It is becoming …

Tumor suppressor p53 plays a central role in tumor suppression. As a transcription factor,
p53 mainly exerts its tumor suppressive function through transcriptional regulation of many …