[HTML][HTML] Towards a safe and effective chlamydial vaccine: lessons from the eye

DCW Mabey, V Hu, RL Bailey, MJ Burton, MJ Holland - Vaccine, 2014 - Elsevier
As well as being the most common bacterial sexually transmitted infection, Chlamydia
trachomatis (Ct) is the leading infectious cause of blindness. The pathogenesis of ocular …

[HTML][HTML] La vacunación en el contexto de la pandemia de COVID-19

Á Díaz-Badillo, GN Garibay-Nieto… - Cirugía y …, 2021 - scielo.org.mx
En esta revisión se describen el historial de vacunación, los diferentes tipos de vacunas y
cómo la cobertura de vacunación se ha visto afectada por la pandemia actual de COVID-19 …

Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation

B Peng, S Zhong, Y Hua, Q Luo, W Dong… - Frontiers in …, 2022 - frontiersin.org
Urogenital tract infections with Chlamydia trachomatis have frequently been detected among
patients diagnosed with sexually transmitted infections, and such infections lead to …

A multi‐subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN‐γ+ CMI responses protects against a genital infection in minipigs

S Bøje, AW Olsen, K Erneholm… - … and Cell Biology, 2016 - Wiley Online Library
Chlamydia is the most widespread sexually transmitted bacterial disease and a prophylactic
vaccine is highly needed. Ideally, this vaccine is required to induce a combined response of …

Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies

A Badamchi-Zadeh, PF McKay, MJ Holland, W Paes… - PLoS …, 2015 - journals.plos.org
Background Ocular infection with Chlamydia trachomatis can cause trachoma, which is the
leading cause of blindness due to infection worldwide. Despite the large-scale …

Multimodal mucosal and systemic immune characterization of a non-human primate trachoma model highlights the critical role of local immunity during acute phase …

E Paulet, V Contreras, M Galhaut… - PLOS Neglected …, 2024 - journals.plos.org
Background Trachoma is a leading cause of infection-related blindness worldwide. This
disease is caused by recurrent Chlamydia trachomatis (Ct) infections of the conjunctiva and …

Human genital antibody-mediated inhibition of Chlamydia trachomatis infection and evidence for ompA genotype-specific neutralization

CM Ardizzone, HL Albritton, RA Lillis, CEL Bagnetto… - PLoS …, 2021 - journals.plos.org
The endocervix, the primary site of Chlamydia trachomatis (Ct) infection in women, has a
unique repertoire of locally synthesized IgG and secretory IgA (SIgA) with contributions from …

Antibodies to Variable Domain 4 Linear Epitopes of the Chlamydia trachomatis Major Outer Membrane Protein Are Not Associated with Chlamydia Resolution or …

AL Collar, AC Linville, SB Core, CM Wheeler… - Msphere, 2020 - journals.asm.org
Chlamydia trachomatis is an obligate intracellular bacterium. C. trachomatis infection is the
most prevalent bacterial sexually transmitted infection and can lead to pelvic inflammatory …

[HTML][HTML] Designing multi-epitope subunit vaccine for ocular trachoma infection using chlamydia trachomatis polymorphic membrane proteins G

LO Ezediuno, OS Onile, EK Oladipo… - Informatics in Medicine …, 2021 - Elsevier
Chlamydia trachomatis serovars A, B, Ba and C are bacteria serovars responsible for the
blinding disease trachoma, the infection affects the upper tarsal conjunctiva of the eye …

Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection

H Pickering, A Teng, N Faal, H Joof, P Makalo… - Scientific reports, 2017 - nature.com
The frequency and duration of Chlamydia trachomatis (Ct) ocular infections decrease with
age, suggesting development of partial immunity. However, there is a lack of clear correlates …