How drug repurposing can advance drug discovery: challenges and opportunities

L Pinzi, N Bisi, G Rastelli - Frontiers in Drug Discovery, 2024 - frontiersin.org
Traditional de novo drug discovery, which typically presents an 11% approval rate from
phase I trials and even higher failure rates in fields like neurodegeneration, often requires …

Drug repositioning: A bibliometric analysis

G Sun, D Dong, Z Dong, Q Zhang, H Fang… - Frontiers in …, 2022 - frontiersin.org
Drug repurposing has become an effective approach to drug discovery, as it offers a new
way to explore drugs. Based on the Science Citation Index Expanded (SCI-E) and Social …

Understanding relationship between topic selection and academic performance of scientific teams based on entity popularity trend

T Zhang, F Tan, C Yu, J Wu, J Xu - Aslib Journal of Information …, 2023 - emerald.com
Purpose Proper topic selection is an essential prerequisite for the success of research. To
study this, this article proposes an important concerned factor of topic selection-topic …

Drug Repurposing using Artificial Intelligence, Molecular Docking, and Hybrid Approaches: A Comprehensive Review in General Diseases vs Alzheimer's Disease

NA Zulhafiz, TC Teoh, AV Chin, SW Chang - Computer Methods and …, 2025 - Elsevier
Background Alzheimer's disease (AD), the most prevalent form of dementia, remains
enigmatic in its origins despite the widely accepted" amyloid hypothesis," which implicates …

Drug repurposing: Insights into current advances and future applications

T Bhatia, S Sharma - Current Medicinal Chemistry, 2025 - benthamdirect.com
Drug development is a complex and expensive process that involves extensive research
and testing before a new drug can be approved for use. This has led to a limited availability …