[HTML][HTML] Phthalate exposure and neurodevelopment: A systematic review and meta-analysis of human epidemiological evidence

EG Radke, JM Braun, RM Nachman… - Environment international, 2020 - Elsevier
Objective We performed a systematic review of the epidemiology literature to identify the
neurodevelopmental effects associated with phthalate exposure. Data sources and study …

Nuclear receptors-mediated endocrine disrupting effects of non-phthalate plasticizers: a review

J Yu, H Zou, T Zhang, J Zhang - Journal of Agricultural and Food …, 2023 - ACS Publications
In 2021, the global market for non-phthalate plasticizers reached $3.1 billion, and it is
projected to grow by 25.8% by 2025. These plasticizers have gained substantial attention as …

Neurotoxicity of ortho-phthalates: recommendations for critical policy reforms to protect brain development in children

SM Engel, HB Patisaul, C Brody… - … journal of public …, 2021 - ajph.aphapublications.org
Robust data from longitudinal birth cohort studies and experimental studies of perinatally
exposed animals indicate that exposure to ortho-phthalates can impair brain development …

Effects of Di-2-ethylhexyl phthalate on central nervous system functions: a narrative review

S Safarpour, M Ghasemi-Kasman… - Current …, 2022 - benthamdirect.com
Background: Phthalates are widely used in the plastics industry. Di-2-Ethylhexyl Phthalate
(DEHP) is one of the most important phthalate metabolites that disrupt the function of …

Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice

M Lei, R Menon, S Manteiga, N Alden, C Hunt… - Msystems, 2019 - journals.asm.org
Exposure to environmental chemicals during windows of development is a potentially
contributing factor in gut microbiota dysbiosis and linked to chronic diseases and …

Chronic di (2-ethylhexyl) phthalate exposure leads to dopaminergic neuron degeneration through mitochondrial dysfunction in C. elegans

ML Huang, PL Yen, CH Chang, VHC Liao - Environmental Pollution, 2022 - Elsevier
Abstract The plasticizer di (2-ethylhexyl) phthalate (DEHP) is frequently detected in the
environment due to the abundance of its use. These levels might be hazardous to human …

Prenatal phthalate exposure and neurodevelopmental differences in twins at 2 years of age

H **ao, L Hu, T Tang, J Zhong, Q Xu, X Cai, F **ang… - BMC Public Health, 2024 - Springer
Background Previous studies of singletons evaluating prenatal phthalate exposure and
early neurodevelopment reported mixed results and the associations could be biased by …

[HTML][HTML] Exposure to low doses of phthalates in male rodents: Effects on reproductive and cognitive behaviors

S Ducroq, V Grange-Messent, S Mhaouty-Kodja - Neuroendocrinology, 2023 - karger.com
Background: The nervous system is a sensitive target for exposure to environmental
endocrine-disrupting compounds (EDC). This vulnerability is particularly important during …

Cognitive and hippocampal effects of adult male mice exposure to environmentally relevant doses of phthalates

S Ducroq, E Duplus, V Grange-Messent… - Environmental …, 2023 - Elsevier
We recently showed that chronic exposure of adult male mice to environmental doses of
DEHP alone or in a phthalate mixture altered blood brain barrier integrity and induced an …

Dibutyl phthalate exposure during gestation and lactation in C57BL/6 mice: Maternal behavior and neurodevelopment in pups

SM Lee, S Jeon, HJ Jeong, BN Kim, Y Kim - Environmental Research, 2020 - Elsevier
Objectives Neurotoxic effects of phthalate during pregnancy on immature brain of the
offspring or mature brains of the mothers remain unclear. We examined the effect of dibutyl …