Rational design of biomaterials to potentiate cancer thermal therapy
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …
eradicate mass lesions that are now defined as cancer. With the development of …
Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Glutathione-depleting nanomedicines for synergistic cancer therapy
X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
Polymeric delivery of therapeutic nucleic acids
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization
Y Yang, L Guo, Z Wang, P Liu, X Liu, J Ding, W Zhou - Biomaterials, 2021 - Elsevier
Infiltration of inflammatory cells, especially the M1 macrophages that secrete various types of
inflammation cytokines, play crucial roles in the pathogenesis of rheumatoid arthritis (RA) …
inflammation cytokines, play crucial roles in the pathogenesis of rheumatoid arthritis (RA) …
A Biodegradable Iridium (III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway
The clinical application of photodynamic therapy is hindered by the high glutathione
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …
Polymeric micelles and cancer therapy: An ingenious multimodal tumor-targeted drug delivery system
Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …
Stimuli-responsive polymeric nanocarriers for drug delivery, imaging, and theragnosis
In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …
and have gained attention from researchers for their potential to efficiently deliver bioactive …