Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

S Alseekh, A Aharoni, Y Brotman, K Contrepois… - Nature …, 2021 - nature.com
Mass spectrometry-based metabolomics approaches can enable detection and
quantification of many thousands of metabolite features simultaneously. However …

Emerging applications of metabolomics in drug discovery and precision medicine

DS Wishart - Nature reviews Drug discovery, 2016 - nature.com
Metabolomics is an emerging'omics' science involving the comprehensive characterization
of metabolites and metabolism in biological systems. Recent advances in metabolomics …

Identification of small molecules using accurate mass MS/MS search

T Kind, H Tsugawa, T Cajka, Y Ma, Z Lai… - Mass spectrometry …, 2018 - Wiley Online Library
Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS
spectra from screening small molecules in fields such as environmental analysis, drug …

Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics

X Shen, R Wang, X **, and metabolite activity analysis using XCMS Online
EM Forsberg, T Huan, D Rinehart, HP Benton… - Nature protocols, 2018 - nature.com
Abstract Systems biology is the study of complex living organisms, and as such, analysis on
a systems-wide scale involves the collection of information-dense data sets that are …

Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives

S Lista, R González-Domínguez, S López-Ortiz… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

S Yuan, H Chu, JFW Chan, ZW Ye, L Wen… - Nature …, 2019 - nature.com
Viruses are obligate intracellular microbes that exploit the host metabolic machineries to
meet their biosynthetic demands, making these host pathways potential therapeutic targets …