Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Mounting evidence highlights the role of adipose tissue in the development of a systemic
inflammatory state that contributes to obesity-associated vasculopathy and cardiovascular …

This review focuses on the mechanisms underlying, and indications for, bariatric surgery in
the reduction of cardiovascular disease (CVD), as well as other expected benefits of this …

The increasing incidence of obesity and the metabolic syndrome is disturbing. The activation
of inflammatory pathways, used normally as host defence, reminds the seriousness of this …

Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

ContextObesity is an independent risk factor for cardiovascular disease, which may be
mediated by increased secretion of proinflammatory cytokines by adipose tissue …

Overweight and obesity affects more than 66% of the adult population and is associated with
a variety of chronic diseases. Weight reduction reduces health risks associated with chronic …

Atherosclerotic disease remains the leading cause of death in industrialized nations despite
major advances in its diagnosis, treatment, and prevention. The increasing epidemic of …

Background Rimonabant, a selective cannabinoid-1 receptor (CB1) blocker, has been
shown to reduce body weight and improve cardiovascular risk factors in obese patients. The …

Obesity adversely affects cardiac function, increases the risk factors for coronary heart
disease, and is an independent risk factor for cardiovascular disease. The risk of develo** …