Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …

Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Background: The increase in the zoonotic epidemic of sporotrichosis caused by Sporothrix
brasiliensis, which started in the late 1990s in Rio de Janeiro and is now found in almost all …

Access to the appropriate tools is crucial for early diagnosis and clinical management of
invasive fungal infections. This Review aims to describe the invasive fungal infection …

Abstract Introduction: Invasive fungal infections (IFIs) in Asia/Pacific are a particular threat to
patients with malignancies, uncontrolled diabetes mellitus or undiagnosed/untreated human …

Disparities in social determinants of health (SDOH) play a significant role in causing health
inequities globally. The physical environment, including housing and workplace …

Abstract Problem/Condition: Coccidioidomycosis, histoplasmosis, and blastomycosis are
underdiagnosed fungal diseases that often mimic bacterial or viral pneumonia and can …

Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America caused by
thermodimorphic fungi of the genus Paracoccidioides. In the last two decades, enhanced …

Background Invasive fungal infections cause millions of infections annually, but diagnosis
remains challenging. There is an increased need for low-cost, easy to use, highly sensitive …