Personalised virtual brain models in epilepsy

V Jirsa, H Wang, P Triebkorn, M Hashemi… - The Lancet …, 2023 - thelancet.com
Individuals with drug-resistant focal epilepsy are candidates for surgical treatment as a
curative option. Before surgery can take place, the patient must have a presurgical …

Neuroimaging and connectomics of drug‐resistant epilepsy at multiple scales: From focal lesions to macroscale networks

S Tavakol, J Royer, AJ Lowe, L Bonilha, JI Tracy… - …, 2019 - Wiley Online Library
Epilepsy is among the most common chronic neurologic disorders, with 30%‐40% of
patients having seizures despite antiepileptic drug treatment. The advent of brain imaging …

Dynamic reconfiguration of functional brain networks during working memory training

K Finc, K Bonna, X He, DM Lydon-Staley… - Nature …, 2020 - nature.com
The functional network of the brain continually adapts to changing environmental demands.
The consequence of behavioral automation for task-related functional network architecture …

Uncovering the biological basis of control energy: Structural and metabolic correlates of energy inefficiency in temporal lobe epilepsy

X He, L Caciagli, L Parkes, J Stiso, TM Karrer… - Science …, 2022 - science.org
Network control theory is increasingly used to profile the brain's energy landscape via
simulations of neural dynamics. This approach estimates the control energy required to …

Disrupted basal ganglia–thalamocortical loops in focal to bilateral tonic-clonic seizures

X He, G Chaitanya, B Asma, L Caciagli, DS Bassett… - Brain, 2020 - academic.oup.com
Focal to bilateral tonic-clonic seizures are associated with lower quality of life, higher risk of
seizure-related injuries, increased chance of sudden unexpected death, and unfavourable …

Repetitive negative thinking in daily life and functional connectivity among default mode, fronto-parietal, and salience networks

DM Lydon-Staley, C Kuehner, V Zamoscik… - Translational …, 2019 - nature.com
Repetitive negative thinking (RNT) is a maladaptive response to sadness and a
transdiagnostic risk-factor. A critical challenge hampering attempts to promote more …

Cortical activation and functional connectivity during the verbal fluency task for adolescent-onset depression: a multi-channel NIRS study

X Liu, F Cheng, S Hu, B Wang, C Hu, Z Zhu… - Journal of psychiatric …, 2022 - Elsevier
Objective Depression disorder is accompanied by cognitive impairments. However, there is
limited research focused on cognitive impairments and their neurological mechanism in …

Thalamus and focal to bilateral seizures: A multiscale cognitive imaging study

L Caciagli, LA Allen, X He, K Trimmel, SB Vos… - Neurology, 2020 - AAN Enterprises
Objective To investigate the functional correlates of recurrent secondarily generalized
seizures in temporal lobe epilepsy (TLE) using task-based fMRI as a framework to test for …

Spatial embedding imposes constraints on neuronal network architectures

J Stiso, DS Bassett - Trends in cognitive sciences, 2018 - cell.com
Recent progress towards understanding circuit function has capitalized on tools from
network science to parsimoniously describe the spatiotemporal architecture of neural …

Disorganization of language and working memory systems in frontal versus temporal lobe epilepsy

L Caciagli, C Paquola, X He, C Vollmar, M Centeno… - Brain, 2023 - academic.oup.com
Cognitive impairment is a common comorbidity of epilepsy and adversely impacts people
with both frontal lobe (FLE) and temporal lobe (TLE) epilepsy. While its neural substrates …