Combining genomics and epidemiology to analyse bi-directional transmission of Mycobacterium bovis in a multi-host system

J Crispell, CH Benton, D Balaz, N De Maio… - elife, 2019 - elifesciences.org
Quantifying pathogen transmission in multi-host systems is difficult, as exemplified in bovine
tuberculosis (bTB) systems, but is crucial for control. The agent of bTB, Mycobacterium bovis …

Animal tuberculosis: Impact of disease heterogeneity in transmission, diagnosis and control

AC Pereira, AC Reis, B Ramos… - … and emerging diseases, 2020 - Wiley Online Library
Animal tuberculosis (TB) in terrestrial mammals is mainly caused by Mycobacterium bovis.
This pathogen is adapted to a wide range of host species, representing a threat to livestock …

One bacillus to rule them all?–Investigating broad range host adaptation in Mycobacterium bovis

AR Allen - Infection, Genetics and Evolution, 2017 - Elsevier
The molecular evolution of intracellular pathogens with regard to host adaptation is an area
of active interest, with the recognition that unraveling the molecular changes which underpin …

Global Distribution and Evolution of Mycobacterium bovis Lineages

CK Zimpel, JSL Patané, ACP Guedes… - Frontiers in …, 2020 - frontiersin.org
Mycobacterium bovis is the main causative agent of zoonotic tuberculosis in humans and
frequently devastates livestock and wildlife worldwide. Previous studies suggested the …

Genetic Evolution of Mycobacterium bovis Causing Tuberculosis in Livestock and Wildlife in France since 1978

A Hauer, K De Cruz, T Cochard, S Godreuil, C Karoui… - PloS one, 2015 - journals.plos.org
To study the dynamics of bovine tuberculosis (bTB) in France, 4,654 M. bovis strains isolated
mainly from livestock and wildlife since 1978 were characterized by spoligoty** and MLVA …

[HTML][HTML] Use of bacterial whole-genome sequencing to investigate local persistence and spread in bovine tuberculosis

H Trewby, D Wright, EL Breadon, SJ Lycett, TR Mallon… - Epidemics, 2016 - Elsevier
Mycobacterium bovis is the causal agent of bovine tuberculosis, one of the most important
diseases currently facing the UK cattle industry. Here, we use high-density whole genome …

Serological test performance for bovine tuberculosis in cattle from herds with evidence of on-going infection in Northern Ireland

L McCallan, C Brooks, C Barry, C Couzens, FJ Young… - PLoS …, 2021 - journals.plos.org
The ability to accurately identify infected hosts is the cornerstone of effective disease control
and eradication programs. In the case of bovine tuberculosis, accurately identifying infected …

Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics, trade movement and co-infection

AW Byrne, J Graham, C Brown, A Donaghy… - BMC Veterinary …, 2017 - Springer
Background Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a
significant problem for livestock industries in many countries worldwide including Northern …