Natural coumarin derivatives activating Nrf2 signaling pathway as lead compounds for the design and synthesis of intestinal anti-inflammatory drugs
LC Di Stasi - Pharmaceuticals, 2023 - mdpi.com
Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor related to stress
response and cellular homeostasis that plays a key role in maintaining the redox system …
response and cellular homeostasis that plays a key role in maintaining the redox system …
Boron compounds exhibit protective effects against aluminum-induced neurotoxicity and genotoxicity: In vitro and in vivo study
Genetic, neuropathological and biochemical investigations have revealed meaningful
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …
Artemisia scoparia and Metabolic Health: Untapped Potential of an Ancient Remedy for Modern Use
A Boudreau, AJ Richard, I Harvey… - Frontiers in …, 2022 - frontiersin.org
Botanicals have a long history of medicinal use for a multitude of ailments, and many
modern pharmaceuticals were originally isolated from plants or derived from …
modern pharmaceuticals were originally isolated from plants or derived from …
Protective effects of esculetin against ovary ischemia–reperfusion injury model in rats
Aims Ovarian ischemia–reperfusion (I/R) injury is a phenomenon that necessitates urgent
intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young …
intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young …
Repro-protective activity of amygdalin and spirulina platensis in niosomes and conventional forms against aluminum chloride–induced testicular challenge in adult …
The male reproductive system is negatively influenced by Al exposure. Al represented a
considerable hazard to men's reproduction capabilities. Amygdalin (AMG) and spirulina …
considerable hazard to men's reproduction capabilities. Amygdalin (AMG) and spirulina …
Transcriptome-based analysis of the toxic effects of aluminum chloride exposure on spermatocytes
P Huixin, W Guangji, H Yanxin, P Yanfang, Y Huixiong… - Toxicology in Vitro, 2023 - Elsevier
Aluminum chloride (AlCl 3) exposure is pervasive in our daily lives. Numerous studies have
demonstrated that exposure to AlCl 3 can lead to male reproductive toxicity. However, the …
demonstrated that exposure to AlCl 3 can lead to male reproductive toxicity. However, the …
Carvacrol showed a curative effect on reproductive toxicity caused by Bisphenol AF via antioxidant, anti-inflammatory and anti-apoptotic properties
Bisphenol AF (BPAF) is an endocrine disruptor, and human exposure to these chemicals is
growing in industrialized nations. BPAF has been demonstrated in studies to have toxic …
growing in industrialized nations. BPAF has been demonstrated in studies to have toxic …
The effect of tyrosol on diclofenac sodium‐induced acute nephrotoxicity in rats
Although diclofenac (DCF) is a nonsteroidal anti‐inflammatory drug that is considered safe,
its chronic use and overdose may show some toxic effects. The protective effect of tyrosol …
its chronic use and overdose may show some toxic effects. The protective effect of tyrosol …
Human amnion membrane-derived mesenchymal stem cells and conditioned medium can ameliorate X-irradiation-induced testicular injury by reducing endoplasmic …
Today, infertility affects 15% of couples and half of this rate is due to reproductive problems
in men. Radiation-induced damage to the testicles causes sterility depending on the dose …
in men. Radiation-induced damage to the testicles causes sterility depending on the dose …
[HTML][HTML] Adansonia digitata L. fruit shell prevents aluminum-induced cognitive impairment and depression in rats
Purpose Aluminum exposure can lead to free radicals production and increased
susceptibility to lipids peroxidation in the central nervous system. The was aimed at …
susceptibility to lipids peroxidation in the central nervous system. The was aimed at …